Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30381748 | 1.00 | HTR6 (0.38) | HTR6MCOLN3L3MBTL1ACHEKLK7 | |
| SCHEMBL25299253 | 0.83 | HTR6 (0.41) | HTR6MCOLN3L3MBTL1HTR2CPOLB | |
| SCHEMBL30381621 | 0.83 | HTR6 (0.41) | HTR6MCOLN3L3MBTL1HTR2CPOLB | |
| SCHEMBL30381550 | 0.80 | ALDH1A1 (0.39) | HTR6L3MBTL1ACHELMNAPOLB | |
| SCHEMBL25428681 | 0.80 | ALDH1A1 (0.39) | HTR6L3MBTL1ACHELMNAPOLB | |
| SCHEMBL25422502 | 0.71 | HTR6 (0.40) | HTR6MCOLN3L3MBTL1ACHEKLK7 | |
| SCHEMBL30294963 | 0.69 | HTR6 (0.39) | HTR6MCOLN3L3MBTL1ACHEKLK7 | |
| Hydrochloric Acid SCHEMBL26911638 | 0.69 | HTR6 (0.56) | HTR6KLK7HTR1A | |
| SCHEMBL26378439 | 0.67 | FFAR2 (0.46) | HTR6ACHEKLK7 | |
| SCHEMBL31472502 | 0.66 | HTR6 (0.43) | HTR6MCOLN3L3MBTL1ACHEKLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107723-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |