Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | SOX18 | P35713 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 2/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1893128 | 0.88 | ALOX15 (0.52) | CYP1A2APPKDM4EALDH1A1MAPT | |
| SCHEMBL16429426 | 0.88 | ALOX15 (0.52) | CYP1A2APPKDM4EALDH1A1MAPT | |
| SCHEMBL15263105 | 0.88 | ALOX15 (0.52) | CYP1A2APPKDM4EALDH1A1MAPT | |
| SCHEMBL25424006 | 0.85 | PTGES (0.49) | PDPK1CYP1A2SOX18ALDH1A1FFAR1 | |
| SCHEMBL25296090 | 0.82 | EGFR (0.46) | CYP1A2APPKDM4EALDH1A1MAPT | |
| SCHEMBL25301865 | 0.82 | ALOX15 (0.51) | CYP1A2APPKDM4EALDH1A1MAPT | |
| SCHEMBL25263708 | 0.81 | IGF1R (0.55) | MAPTPOLBGAAHTTFFAR1 | |
| SCHEMBL25300688 | 0.80 | ALOX15 (0.54) | CYP1A2APPKDM4EALDH1A1MAPT | |
| SCHEMBL25261511 | 0.79 | ALOX15 (0.56) | CYP1A2APPKDM4EALDH1A1MAPT | |
| SCHEMBL25255253 | 0.78 | ALOX15 (0.55) | CYP1A2APPKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423429-B1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIV DE MONCTON (CA) | 2023-07-12 | — | — | EP | claimed |