Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SOX18 | P35713 | 1/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25428154 | 0.85 | PDPK1 (0.49) | PDPK1CYP1A2CYP3A4CYP2C9FFAR1 | |
| SCHEMBL28251651 | 0.85 | PTGS2 (0.52) | PTGESALOX5PPARGPDPK1CYP1A2 | |
| SCHEMBL19437161 | 0.82 | CYP3A4 (0.68) | PTGESALOX5PPARGCYP3A4CYP2C9 | |
| SCHEMBL584959 | 0.82 | CYP3A4 (0.68) | PTGESALOX5PPARGCYP3A4CYP2C9 | |
| SCHEMBL19437149 | 0.82 | CYP3A4 (0.68) | PTGESALOX5PPARGCYP3A4CYP2C9 | |
| SCHEMBL16429426 | 0.82 | ALOX15 (0.52) | ALOX5CYP1A2CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL1893128 | 0.82 | ALOX15 (0.52) | ALOX5CYP1A2CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL15263105 | 0.82 | ALOX15 (0.52) | ALOX5CYP1A2CYP3A4CYP2C9ALDH1A1 | |
| SCHEMBL25255448 | 0.81 | PLAAT3 (0.50) | PTGESALOX5PPARGPDPK1CYP3A4 | |
| SCHEMBL7514687 | 0.80 | TBXAS1 (0.47) | PPARGCYP3A4CYP2C9RELAGLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423429-B1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIV DE MONCTON (CA) | 2023-07-12 | — | — | EP | claimed |