Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | BAD | Q92934 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | TACR2 | P21452 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25956089 | 0.90 | PDPK1 (0.40) | NOD2NOD1TRPV1 | |
| SCHEMBL30544106 | 0.90 | PDPK1 (0.40) | NOD2NOD1TRPV1 | |
| SCHEMBL30544057 | 0.88 | SCN9A (0.44) | TRPV1SCN8ASCN10AFFAR4BCL2L1 | |
| SCHEMBL25952320 | 0.88 | SCN9A (0.44) | TRPV1SCN8ASCN10AFFAR4BCL2L1 | |
| SCHEMBL30544026 | 0.86 | TRPV1 (0.39) | TRPV1SCN8ASCN10ASCN5ASCN9A | |
| SCHEMBL25428113 | 0.86 | TRPV1 (0.39) | TRPV1SCN8ASCN10ASCN5ASCN9A | |
| SCHEMBL25429484 | 0.86 | SCN8A (0.43) | TRPV1SCN8ASCN10AFFAR4SCN5A | |
| SCHEMBL25429756 | 0.84 | ICMT (0.39) | TRPV1SCN8ASCN10AFFAR4SCN5A | |
| SCHEMBL30544045 | 0.84 | ICMT (0.39) | TRPV1SCN8ASCN10AFFAR4SCN5A | |
| SCHEMBL25954187 | 0.80 | GRIN2B (0.50) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |