Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 17/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25429484 | 0.84 | SCN8A (0.43) | TRPV1 | |
| SCHEMBL25429756 | 0.83 | ICMT (0.39) | TRPV1 | |
| SCHEMBL30544045 | 0.83 | ICMT (0.39) | TRPV1 | |
| SCHEMBL30544057 | 0.83 | SCN9A (0.44) | TRPV1 | |
| SCHEMBL25952320 | 0.83 | SCN9A (0.44) | TRPV1 | |
| SCHEMBL25429629 | 0.82 | TRPV1 (0.46) | TRPV1 | |
| SCHEMBL25428113 | 0.81 | TRPV1 (0.39) | TRPV1 | |
| SCHEMBL30544026 | 0.81 | TRPV1 (0.39) | TRPV1 | |
| SCHEMBL25429273 | 0.80 | NOD2 (0.37) | TRPV1 | |
| SCHEMBL30544106 | 0.79 | PDPK1 (0.40) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |