Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 5/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | PRKACG | P22612 | 1/20 | 0.33 |
| ▸ | PRKACB | P22694 | 1/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25428113 | 1.00 | TRPV1 (0.39) | TRPV1SCN9ASCN5ACAMK2DBRD4 | |
| SCHEMBL25952320 | 0.91 | SCN9A (0.44) | TRPV1SCN9ASCN5ABRD4ERBB2 | |
| SCHEMBL30544057 | 0.91 | SCN9A (0.44) | TRPV1SCN9ASCN5ABRD4ERBB2 | |
| SCHEMBL25429484 | 0.89 | SCN8A (0.43) | TRPV1SCN9ASCN5ABRD4ERBB2 | |
| SCHEMBL30544045 | 0.87 | ICMT (0.39) | TRPV1SCN9ASCN5AFEN1SCN8A | |
| SCHEMBL25429756 | 0.87 | ICMT (0.39) | TRPV1SCN9ASCN5AFEN1SCN8A | |
| SCHEMBL25429273 | 0.86 | NOD2 (0.37) | TRPV1SCN9ASCN5ASCN8ASCN10A | |
| SCHEMBL25429629 | 0.84 | TRPV1 (0.46) | TRPV1SCN9ASCN5ABRD4 | |
| SCHEMBL30544106 | 0.83 | PDPK1 (0.40) | TRPV1CAMK2D | |
| SCHEMBL25956089 | 0.83 | PDPK1 (0.40) | TRPV1CAMK2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |