Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | IL1B | P01584 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 4/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25430058 | 1.00 | HTR1A (0.34) | HTR1AHTR7MCHR1SIGMAR1TNF | |
| SCHEMBL25346369 | 0.89 | TNF (0.34) | TNFIL1BDDB1CRBNIKZF3 | |
| SCHEMBL28030943 | 0.83 | DDB1 (0.38) | TNFIL1BDDB1CRBNIKZF3 | |
| SCHEMBL25433270 | 0.82 | LMNA (0.33) | TNFIL1BDDB1CRBNIKZF3 | |
| SCHEMBL25346279 | 0.81 | SIGMAR1 (0.41) | HTR1AHTR7SIGMAR1MC4RKCNH2 | |
| SCHEMBL25345447 | 0.81 | SIGMAR1 (0.41) | HTR1AHTR7SIGMAR1MC4RKCNH2 | |
| SCHEMBL28030946 | 0.80 | DDB1 (0.39) | TNFIL1BDDB1CRBNIKZF3 | |
| SCHEMBL25346645 | 0.78 | PIK3CD (0.35) | KCNH2HRH3 | |
| SCHEMBL28822138 | 0.78 | HRH3 (0.39) | TNFIL1BDDB1CRBNIKZF3 | |
| SCHEMBL27936623 | 0.78 | DDB1 (0.51) | TNFIL1BDDB1CRBNIKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023151635-A1 | COMPOUND BASED ON QUINAZOLINE-SUBSTITUTED GLUTARIMIDE SKELETON AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2023-08-17 | — | — | WO | claimed |