Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25954052 | 0.86 | TRPV1 (0.37) | TRPV1MCHR1KDM2BKDM4CSCN9A | |
| SCHEMBL30544122 | 0.86 | TRPV1 (0.37) | TRPV1MCHR1KDM2BKDM4CSCN9A | |
| SCHEMBL25430689 | 0.81 | PDE10A (0.42) | TRPV1MCHR1KDM2BKDM4C | |
| SCHEMBL25429043 | 0.77 | SLC6A2 (0.38) | TRPV1MCHR1SCN9ASCN5ACYP1A2 | |
| SCHEMBL25430317 | 0.77 | HSD17B10 (0.53) | TRPV1EPHX2MAPK1KIF11 | |
| SCHEMBL25430344 | 0.73 | TRPV1 (0.41) | TRPV1MAPK1KIF11 | |
| Hydrochloric Acid SCHEMBL10631649 | 0.72 | KIF11 (0.47) | SCN9ASCN5AKIF11 | |
| SCHEMBL25974048 | 0.71 | TRPV1 (0.37) | TRPV1KIF11 | |
| SCHEMBL25340553 | 0.70 | KIF11 (0.50) | TRPV1CYP1A2CYP3A4CYP2C9HPGD | |
| SCHEMBL25341274 | 0.70 | KIF11 (0.50) | TRPV1HPGDMAPK1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |