Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25433941 | 0.85 | PDE10A (0.35) | PDE10ATRPV1 | |
| SCHEMBL25429595 | 0.81 | TRPV1 (0.37) | TRPV1MCHR1KDM2BKDM4C | |
| SCHEMBL30544064 | 0.79 | PDE10A (0.43) | PDE10ATRPV1KDM2BKDM4C | |
| SCHEMBL25431600 | 0.79 | PDE10A (0.43) | PDE10ATRPV1KDM2BKDM4C | |
| SCHEMBL25429629 | 0.77 | TRPV1 (0.46) | TRPV1MCHR1 | |
| SCHEMBL25429893 | 0.77 | HSD17B10 (0.54) | PDE10ATRPV1MAOAMAOB | |
| Hydrochloric Acid SCHEMBL10631649 | 0.73 | KIF11 (0.47) | MAT2A | |
| SCHEMBL25340961 | 0.73 | TRPV1 (0.45) | PDE10ATRPV1CSF1R | |
| SCHEMBL25340448 | 0.72 | TRPV1 (0.38) | PDE10ATRPV1 | |
| SCHEMBL25973973 | 0.71 | THRB (0.41) | PDE10ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |