Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 5-Methylfurfural SCHEMBL14059950 | 0.86 | ALDH1A1 (0.47) | CHRM2MEN1KMT2ACHRM4CHRM5 | |
| SCHEMBL2540847 | 0.85 | ALDH1A1 (0.35) | KMT2AMAPTPOLBTDP1ALDH1A1 | |
| 5-Methylfurfural SCHEMBL28591951 | 0.81 | ALDH1A1 (0.42) | MEN1KMT2AMAPTALOX5POLB | |
| SCHEMBL182997 | 0.80 | CHRM2 (0.44) | CHRM2MEN1KMT2ACHRM4CHRM5 | |
| SCHEMBL16197726 | 0.76 | CHRM2 (0.52) | CHRM2MEN1KMT2ACHRM4CHRM5 | |
| SCHEMBL28835757 | 0.76 | ALDH1A1 (0.31) | ALDH1A1TSHRHPGD | |
| SCHEMBL27614569 | 0.76 | ALDH1A1 (0.31) | ALDH1A1TSHR | |
| SCHEMBL2541640 | 0.76 | ALDH1A1 (0.57) | MEN1KMT2ACYP2C9MAPTPOLB | |
| SCHEMBL28109516 | 0.76 | ALDH1A1 (0.31) | ALDH1A1TSHR | |
| SCHEMBL2544210 | 0.76 | ALDH1A1 (0.52) | CYP2C9MAPTPOLBTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10696645-B2 | Method for producing purified dialkyl-furan-2,5-dicarboxylate | EASTMAN CHEMICAL COMPANY (US) | 2020-06-30 | — | — | US | disclosed |
| US-20190023676-A1 | METHOD FOR PRODUCING PURIFIED DIALKYL-FURAN-2,5-DICARBOXYLATE | EASTMAN CHEMICAL COMPANY (US) | 2019-01-24 | — | — | US | disclosed |
| US-8324409-B2 | Efficient method for preparing 2,5-dimethylfuran | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-12-04 | — | — | US | disclosed |
| US-8324409-B2 | Efficient method for preparing 2,5-dimethylfuran | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-12-04 | — | — | US | disclosed |
| US-8324409-B2 | Efficient method for preparing 2,5-dimethylfuran | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-12-04 | — | — | US | disclosed |
| US-20110263880-A1 | EFFICIENT METHOD FOR PREPARING 2,5-DIMETHYLFURAN | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2011-10-27 | — | — | US | disclosed |
| US-20110263880-A1 | EFFICIENT METHOD FOR PREPARING 2,5-DIMETHYLFURAN | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2011-10-27 | — | — | US | disclosed |
| US-20110263880-A1 | EFFICIENT METHOD FOR PREPARING 2,5-DIMETHYLFURAN | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10696645-B2 | Method for producing purified dialkyl-furan-2,5-dicarboxylate | DDC, ACACA, ACACB | CHRM2 2494/4885MEN1 3993/4885KMT2A 2257/4885 |
| US-20190023676-A1 | METHOD FOR PRODUCING PURIFIED DIALKYL-FURAN-2,5-DICARBOXYLATE | DDC, ACACA, ACACB | CHRM2 2494/4885MEN1 3993/4885KMT2A 2257/4885 |
| US-20110263880-A1 | EFFICIENT METHOD FOR PREPARING 2,5-DIMETHYLFURAN | DERA, ALDOA, DPYD | CHRM2 3640/4885MEN1 1142/4885KMT2A 855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.