Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 3/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2540847 | 0.89 | ALDH1A1 (0.35) | ALDH1A1TSHRTDP1MAPTSMN1; SMN2 | |
| SCHEMBL28273403 | 0.82 | ALDH1A1 (0.38) | ALDH1A1TSHR | |
| SCHEMBL28835757 | 0.80 | ALDH1A1 (0.31) | ALDH1A1TSHRSMN1; SMN2HPGD | |
| SCHEMBL28109516 | 0.80 | ALDH1A1 (0.31) | ALDH1A1TSHR | |
| SCHEMBL19248471 | 0.79 | CA2 (0.38) | TDP1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL17485950 | 0.78 | SMN1; SMN2 (0.33) | ALDH1A1TSHRTDP1MAPTSMN1; SMN2 | |
| SCHEMBL19248474 | 0.77 | ALDH1A1 (0.49) | ALDH1A1TSHRTDP1KDM4EMAPT | |
| SCHEMBL17537995 | 0.76 | ALDH1A1 (0.45) | ALDH1A1TSHRTDP1KDM4EMAPT | |
| SCHEMBL2541640 | 0.76 | ALDH1A1 (0.57) | ALDH1A1TSHRTDP1KDM4EMAPT | |
| SCHEMBL2542967 | 0.76 | CHRM2 (0.44) | ALDH1A1TSHRTDP1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324409-B2 | Efficient method for preparing 2,5-dimethylfuran | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-12-04 | — | — | US | disclosed |
| US-8324409-B2 | Efficient method for preparing 2,5-dimethylfuran | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-12-04 | — | — | US | disclosed |
| US-8324409-B2 | Efficient method for preparing 2,5-dimethylfuran | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2012-12-04 | — | — | US | disclosed |
| US-20110263880-A1 | EFFICIENT METHOD FOR PREPARING 2,5-DIMETHYLFURAN | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2011-10-27 | — | — | US | disclosed |
| US-20110263880-A1 | EFFICIENT METHOD FOR PREPARING 2,5-DIMETHYLFURAN | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2011-10-27 | — | — | US | disclosed |
| US-20110263880-A1 | EFFICIENT METHOD FOR PREPARING 2,5-DIMETHYLFURAN | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263880-A1 | EFFICIENT METHOD FOR PREPARING 2,5-DIMETHYLFURAN | DERA, ALDOA, DPYD | ALDH1A1 99/4885TSHR 4737/4885TDP1 2148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.