Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25427626 | 0.86 | HSD17B10 (0.51) | HSD17B10TRPV1TRPA1ALDH1A1MAOA | |
| SCHEMBL25429394 | 0.85 | HSD17B10 (0.52) | HSD17B10TRPV1TRPA1PDE10A | |
| SCHEMBL25430317 | 0.80 | HSD17B10 (0.53) | HSD17B10TRPV1TRPA1ALDH1A1 | |
| SCHEMBL25430689 | 0.77 | PDE10A (0.42) | TRPV1MAOAMAOBPDE10A | |
| SCHEMBL25429720 | 0.77 | HSD17B10 (0.55) | HSD17B10TRPV1ALDH1A1 | |
| SCHEMBL25340961 | 0.73 | TRPV1 (0.45) | TRPV1BRAFKDRMAPK14TNNI3K | |
| SCHEMBL9400251 | 0.72 | HSD17B10 (1.00) | HSD17B10ALDH1A1 | |
| SCHEMBL25973973 | 0.72 | THRB (0.41) | TRPV1PDE10A | |
| SCHEMBL25428892 | 0.72 | TRPV1 (0.37) | TRPV1PIK3CAPDE10A | |
| SCHEMBL30544130 | 0.72 | TRPV1 (0.37) | TRPV1PIK3CAPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146511-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |