Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 3/20 | 0.42 |
| ▸ | CMA1 | P23946 | 2/20 | 0.42 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.39 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | BCL6 | P41182 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30623134 | 1.00 | CA9 (0.44) | CA9AHRCMA1EIF2AK2PKM | |
| SCHEMBL26023073 | 0.86 | AHR (0.43) | AHRCMA1EIF2AK2PKMCRBN | |
| SCHEMBL395800 | 0.79 | KIF11 (0.52) | CA9AHRCMA1EIF2AK2CRBN | |
| Methylamine SCHEMBL28015139 | 0.77 | CA9 (0.66) | CA9AHRCMA1EIF2AK2CRBN | |
| SCHEMBL398137 | 0.77 | CA9 (0.70) | CA9AHRCMA1EIF2AK2CRBN | |
| SCHEMBL30468520 | 0.77 | CA9 (0.70) | CA9AHRCMA1EIF2AK2CRBN | |
| Hydrochloric Acid SCHEMBL9833199 | 0.75 | CA9 (0.68) | CA9AHRCMA1EIF2AK2CRBN | |
| SCHEMBL30185072 | 0.73 | CRBN (0.47) | AHRCMA1EIF2AK2PKMCRBN | |
| SCHEMBL15521357 | 0.73 | AHR (0.56) | AHRCMA1EIF2AK2PKMCRBN | |
| SCHEMBL31139506 | 0.72 | CRBN (0.60) | CRBNMAPTSMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4475837-A2 | TRKB LIGAND CONJUGATED COMPOUNDS AND USES THEREOF | Adarx Pharmaceuticals, Inc. (US) | 2024-12-18 | — | — | EP | disclosed |
| WO-2023154896-A2 | TRKB LIGAND CONJUGATED COMPOUNDS AND USES THEREOF | ADARX PHARMACEUTICALS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |
| WO-2023154896-A2 | TRKB LIGAND CONJUGATED COMPOUNDS AND USES THEREOF | ADARX PHARMACEUTICALS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |