Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA7 | P43166 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7920956 | 0.79 | POLB (0.33) | POLBOPRM1SMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL3623072 | 0.77 | OPRM1 (0.40) | OPRM1SMN1; SMN2OPRD1OPRK1SLC22A1 | |
| SCHEMBL700823 | 0.73 | GRM4 (0.31) | — | |
| SCHEMBL1701987 | 0.73 | MAPT (0.39) | POLBOPRM1SMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL28872247 | 0.71 | CACNA1F (0.39) | OPRM1SMN1; SMN2OPRD1MEN1KMT2A | |
| SCHEMBL10442548 | 0.70 | TSHR (0.35) | OPRM1SMN1; SMN2OPRD1OPRK1SLC22A1 | |
| SCHEMBL9490217 | 0.69 | PIN1 (0.31) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL10393568 | 0.67 | BRD4 (0.45) | POLBOPRM1SMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL3775595 | 0.67 | POLB (0.36) | POLBOPRM1SMN1; SMN2OPRD1OPRK1 | |
| SCHEMBL4921470 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044098-B2 | Use of e.g. 2,4-dihydroxybenzoic acid or 3,4,5-trihydroxybenzoic acid or esters thereof; hepatitis B virus (HBV), papillomavirus and/or herpes virus | SHENGHUA GUANGZHOU PHARMACEUTICAL SCIENCE & TECHNOLOGY CO., LTD. (CN) | 2011-10-25 | — | — | US | disclosed |
| EP-1930002-A1 | USE OF HYDROXYBENZOIC ACID ESTER AND ANALOGUES FOR THE MANUFACTURE OF A MENDICAMENT FOR THE PREVENTION AND TREATMENT OF VIRUS INFECTION | SHENGHUA (GUANGZHOU) PHARMACEUTICAL SCIENCE & (CN) | 2008-06-11 | — | — | EP | disclosed |
| US-20080119550-A1 | Use of e.g. 2,4-dihydroxybenzoic acid or 3,4,5-trihydroxybenzoic acid or esters thereof; hepatitis B virus (HBV), papillomavirus and/or herpes virus | SHENGHUA GUANGZHOU PHARMACEUTICAL SCIENCE & TECHNOLOGY CO., LTD. (CN) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119550-A1 | Use of e.g. 2,4-dihydroxybenzoic acid or 3,4,5-trihydroxybenzoic acid or esters thereof; hepatitis B virus (HBV), papillomavirus and/or herpes virus | ETV1, ETV6, CYP8B1 | POLB 300/4885OPRM1 4672/4885SMN1; SMN2 4858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.