Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PNLIP | P16233 | 3/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | ATP1A1 | P05023 | 7/20 | 0.37 |
| ▸ | ATP1B1 | P05026 | 7/20 | 0.37 |
| ▸ | ATP1A3 | P13637 | 7/20 | 0.37 |
| ▸ | ATP1B2 | P14415 | 7/20 | 0.37 |
| ▸ | ATP1A2 | P50993 | 7/20 | 0.37 |
| ▸ | ATP1B3 | P54709 | 7/20 | 0.37 |
| ▸ | FXYD2 | P54710 | 7/20 | 0.37 |
| ▸ | ATP1A4 | Q13733 | 7/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31592754 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL25437972 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL30585235 | 1.00 | ALDH1A1 (0.41) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL30585226 | 0.90 | RPS6KA5 (0.38) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL25397289 | 0.84 | PNLIP (0.50) | CYP3A4PNLIPRPS6KA5MAPKAPK2PTPN2 | |
| SCHEMBL25397549 | 0.84 | PNLIP (0.50) | CYP3A4PNLIPRPS6KA5MAPKAPK2PTPN2 | |
| SCHEMBL30585240 | 0.84 | PNLIP (0.50) | CYP3A4PNLIPRPS6KA5MAPKAPK2PTPN2 | |
| SCHEMBL25394646 | 0.83 | PTPN2 (0.43) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL31592740 | 0.83 | PTPN2 (0.43) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL25396651 | 0.83 | PTPN2 (0.43) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250171391-A1 | PROCESS FOR PREPARING OCTAHYDRO-2(1H)-NAPHTHALENONE DERIVATIVES | FIRMENICH SA (CH) | 2025-05-29 | — | — | US | disclosed |
| EP-4479369-A1 | PROCESS FOR PREPARING OCTAHYDRO-2(1H)-NAPHTHALENONE DERIVATIVES | Firmenich SA (CH) | 2024-12-25 | — | — | EP | disclosed |
| WO-2023156429-A1 | PROCESS FOR PREPARING OCTAHYDRO-2(1H)-NAPHTHALENONE DERIVATIVES | FIRMENICH SA (CH) | 2023-08-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250171391-A1 | PROCESS FOR PREPARING OCTAHYDRO-2(1H)-NAPHTHALENONE DERIVATIVES | POR, NDUFV1, NDUFV2 | ALDH1A1 173/4885CYP3A4 12/4885CYP2C9 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.