Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | BLM | P54132 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.33 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.33 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19707 | 0.80 | PTPN11 (0.54) | NPC1RAB9APTPN11KDM4EHTT | |
| Bromobenzene SCHEMBL5795843 | 0.65 | ALDH1A1 (0.50) | ALDH1A1LMNAHDAC3HDAC1HDAC2 | |
| Bromobenzene SCHEMBL27752036 | 0.64 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL300347 | 0.63 | RAB9A (0.52) | NPC1RAB9AKDM4EGAAHTT | |
| SCHEMBL21815099 | 0.63 | LMNA (0.40) | NPC1RAB9AKDM4EGAAHTT | |
| SCHEMBL2033642 | 0.62 | — | — | |
| SCHEMBL11305 | 0.62 | — | — | |
| Acridine SCHEMBL25416084 | 0.61 | ALDH1A1 (0.54) | MAPTALDH1A1HPGD | |
| SCHEMBL22798780 | 0.60 | PDE10A (0.43) | NPC1RAB9AGAAHTTCCNC | |
| Benzene SCHEMBL4758974 | 0.60 | TSHR (0.44) | HTTMAPTMEN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078824-A1 | SPIRO-(INDANE-FLUORENE) TYPE COMPOUNDS AND THEIR USE IN ORGANIC ELECTRONICS | DOTTIKON ES HOLDING AG (CH) | 2023-05-11 | — | — | WO | disclosed |