Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PPOX | P50336 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31118393 | 1.00 | KMO (0.40) | KMOEGLN2S100A4GRM2PTGS2 | |
| SCHEMBL8974517 | 0.86 | KMO (0.42) | KMOEGLN2S100A4GRM2PTGS2 | |
| SCHEMBL30688105 | 0.85 | KMO (0.37) | KMOEGLN2S100A4GRM2PTGS2 | |
| SCHEMBL25432867 | 0.85 | KMO (0.37) | KMOEGLN2S100A4GRM2PTGS2 | |
| SCHEMBL30598347 | 0.83 | S100A4 (0.46) | KMOEGLN2S100A4GRM2HSD11B1 | |
| SCHEMBL23638850 | 0.83 | S100A4 (0.46) | KMOEGLN2S100A4GRM2HSD11B1 | |
| SCHEMBL17514808 | 0.80 | KMO (0.39) | KMOEGLN2S100A4GRM2PTGS2 | |
| SCHEMBL27075579 | 0.79 | CA1 (0.42) | PTGS2 | |
| SCHEMBL25432559 | 0.78 | KMO (0.38) | KMOEGLN2S100A4GRM2HSD11B1 | |
| SCHEMBL17514897 | 0.77 | KMO (0.37) | KMOEGLN2S100A4GRM2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260068883-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2026-03-12 | — | — | US | disclosed |
| US-12302900-B2 | Protoporphyrinogen oxidase inhibitors | ENKO CHEM, INC. (US) | 2025-05-20 | — | — | US | disclosed |
| EP-4463000-A2 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | Enko Chem, Inc. (US) | 2024-11-20 | — | — | EP | disclosed |
| WO-2024192147-A2 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2024-09-19 | — | — | WO | disclosed |
| CN-118525002-A | Protoporphyrinogen oxidase inhibitors | 恩科化学公司 | 2024-08-20 | — | — | CN | disclosed |
| US-20240130365-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2024-04-25 | — | — | US | disclosed |
| US-11889833-B2 | Protoporphyrinogen oxidase inhibitors | ENKO CHEM, INC. (US) | 2024-02-06 | — | — | US | disclosed |
| US-20230354809-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2023-11-09 | — | — | US | disclosed |
| US-20230354809-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2023-11-09 | — | — | US | disclosed |
| US-20230354809-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2023-11-09 | — | — | US | disclosed |
| WO-2023137309-A2 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | ENKO CHEM, INC. (US) | 2023-07-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11889833-B2 | Protoporphyrinogen oxidase inhibitors | PPOX, PNPO, PPIF | KMO 152/4885EGLN2 695/4885S100A4 2879/4885 |
| US-20240130365-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | PPOX, PNPO, PPIF | KMO 152/4885EGLN2 695/4885S100A4 2879/4885 |
| US-12302900-B2 | Protoporphyrinogen oxidase inhibitors | PPOX, PNPO, PPIF | KMO 152/4885EGLN2 695/4885S100A4 2879/4885 |
| US-20260068883-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | PPOX, CYC1, CBR3 | KMO 263/4885EGLN2 731/4885S100A4 3258/4885 |
| US-20230354809-A1 | PROTOPORPHYRINOGEN OXIDASE INHIBITORS | PPOX, PNPO, PPIF | KMO 152/4885EGLN2 695/4885S100A4 2879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.