Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PAK4 | O96013 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | LTK | P29376 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21040127 | 0.82 | PTGS2 (0.47) | PTGS2PTGS1MAPK14DAPK3PRKD3 | |
| SCHEMBL288550 | 0.79 | ALDH1A1 (0.42) | ENPP1PTGS2MAPK9CLK4ALDH1A1 | |
| SCHEMBL30114855 | 0.79 | ALDH1A1 (0.42) | ENPP1PTGS2MAPK9CLK4ALDH1A1 | |
| SCHEMBL2678819 | 0.78 | ALDH1A1 (0.41) | LCKCSF1RFGFR1PRKACAKDR | |
| SCHEMBL10353109 | 0.78 | APP (0.43) | DAPK3ABL1PRKACALTKKDR | |
| SCHEMBL5966326 | 0.78 | ABL1 (0.47) | ABL1HSD17B1HSD17B2ALDH1A1 | |
| SCHEMBL380556 | 0.78 | ENPP1 (0.41) | ENPP1PTGS2PTGS1ACHE | |
| SCHEMBL1443992 | 0.78 | PDCD1 (0.43) | ENPP1PTGS2PTGS1MAPK14DAPK3 | |
| SCHEMBL8393810 | 0.77 | ALDH1A1 (0.41) | ENPP1MAP4K4CSF1RFGFR1LTK | |
| SCHEMBL5803876 | 0.77 | ENPP1 (0.41) | ENPP1PTGS2PTGS1MAPK14DAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2134768-B1 | PROTON CONDUCTING AROMATIC POLYETHER TYPE COPOLYMERS BEARING MAIN AND SIDE CHAIN PYRIDINE GROUPS AND USE THEREOF IN PROTON EXCHANGE MEMBRANE FUEL CELLS | ADVENT TECHNOLOGIES (GR) | 2010-09-15 | — | — | EP | claimed |
| EP-2880079-A1 | SYNTHESIS OF AND CURING ADDITIVES FOR PHTHALONITRILES | The Government of the U.S.A., as represented by The Secretary of the Navy (US) | 2015-06-10 | — | — | EP | disclosed |
| US-8969434-B2 | Polymeric compositions containing microspheres | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2015-03-03 | — | — | US | disclosed |
| US-8946321-B2 | Polymeric compositions containing microspheres | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2015-02-03 | — | — | US | disclosed |
| WO-2014021946-A1 | SYNTHESIS OF AND CURING ADDITIVES FOR PHTHALONITRILES | THE GOV. OF THE U.S. OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2014-02-06 | — | — | WO | disclosed |
| US-20110263775-A1 | PHOSPHINE OXIDE CONTAINING PHTHALONITRILES | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2011-10-27 | — | — | US | disclosed |
| US-20080255287-A1 | PHOSPHINE OXIDE CONTAINING PHTHALONITRILES | THE GOVERNMENT OF THE US, AS REPRESENTED BY THE SECRECTARY OF THE NAVY (US) | 2008-10-16 | — | — | US | disclosed |
| EP-1473325-B1 | High strength material based on vinylester and/or epoxyde resin, preparation process, composite material and use | ASTRIUM SAS (FR) | 2007-12-19 | — | — | EP | disclosed |
| EP-1473325-A1 | High strength material based on vinylester and/or epoxyde resin, preparation process, composite material and use | EADS SPACE Transportation SA (FR) | 2004-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255287-A1 | PHOSPHINE OXIDE CONTAINING PHTHALONITRILES | PHOSPHO1, PBRM1, PFAS | ENPP1 1266/4885PTGS2 3477/4885PTGS1 3304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.