Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | BCR | P11274 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28696774 | 0.84 | ABCG2 (0.43) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28711726 | 0.80 | KIF11 (0.38) | NPC1MAPK1RAB9ASMN1; SMN2ESR2 | |
| SCHEMBL28713305 | 0.79 | ESR1 (0.32) | ESR2ESR1 | |
| SCHEMBL25226274 | 0.77 | ESR2 (0.52) | MEN1KMT2ANPC1TP53MAPK1 | |
| SCHEMBL29227269 | 0.74 | IDO1 (0.38) | MEN1KMT2ANPC1TP53MAPK1 | |
| SCHEMBL13145980 | 0.74 | CA1 (0.44) | NPC1CASP3RAB9ASMN1; SMN2SENP7 | |
| SCHEMBL30554744 | 0.73 | NTRK1 (0.38) | MEN1KMT2ANPC1CASP3RAB9A | |
| SCHEMBL29227272 | 0.73 | NTRK1 (0.38) | MEN1KMT2ANPC1CASP3RAB9A | |
| SCHEMBL25271741 | 0.72 | GAA (0.48) | MEN1KMT2ANPC1TP53MAPK1 | |
| SCHEMBL30307098 | 0.70 | NTRK1 (0.47) | MEN1KMT2ANPC1TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023103611-A1 | BROMOPYRENE INTERMEDIATE AND DERIVATIVES THEREOF, PREPARATION METHOD, AND USE | 广东工业大学 | 2023-06-15 | — | — | WO | disclosed |
| CN-114149307-A | Bromopyrene intermediate and derivative, preparation method and application thereof | 广东工业大学 | 2022-03-08 | — | — | CN | disclosed |