Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23419446 | 0.86 | — | — | |
| SCHEMBL23419423 | 0.79 | CA2 (0.35) | SMN1; SMN2CA2TSHR | |
| SCHEMBL23419422 | 0.77 | CA2 (0.34) | SMN1; SMN2CA12CA2CA3CA4 | |
| SCHEMBL23453256 | 0.76 | TSHR (0.36) | SMN1; SMN2KDM4ETSHR | |
| SCHEMBL23453255 | 0.76 | LOXL2 (0.31) | — | |
| SCHEMBL25997237 | 0.76 | CA2 (0.33) | SMN1; SMN2CA12CA2CA3CA4 | |
| SCHEMBL23419305 | 0.75 | PAOX (0.44) | SMN1; SMN2GRIN1GRIN2AGRIN2B | |
| SCHEMBL23392477 | 0.75 | PAOX (0.44) | SMN1; SMN2GRIN1GRIN2AGRIN2B | |
| SCHEMBL23453250 | 0.75 | TSHR (0.38) | SMN1; SMN2KDM4ETSHR | |
| SCHEMBL23419457 | 0.74 | KDM4E (0.39) | KDM4EGRIN1GRIN2AGRIN2BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250290137-A1 | SUBSTITUTED COUMARIN DYES AND USES AS FLUORESCENT LABELS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2025-09-18 | — | — | US | disclosed |
| US-12351871-B2 | Substituted coumarin dyes and uses as fluorescent labels | ILLUMINA CAMBRIDGE LIMITED (GB) | 2025-07-08 | — | — | US | disclosed |
| US-20240271209-A1 | SUBSTITUTED COUMARIN DYES AND USES AS FLUORESCENT LABELS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2024-08-15 | — | — | US | disclosed |
| US-11981964-B2 | Substituted coumarin dyes and uses as fluorescent labels | ILLUMINA CAMBRIDGE LIMITED (GB) | 2024-05-14 | — | — | US | disclosed |
| EP-4188921-A1 | SUBSTITUTED COUMARIN DYES AND USES AS FLUORESCENT LABELS | Illumina Cambridge Limited (GB) | 2023-06-07 | — | — | EP | disclosed |
| CN-115867544-A | Substituted coumarin dyes and their use as fluorescent labels | 伊鲁米纳剑桥有限公司 | 2023-03-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11981964-B2 | Substituted coumarin dyes and uses as fluorescent labels | FBL, DUT, PHAX | SMN1; SMN2 4563/4885KDM4E 3407/4885GRIN1 4848/4885 |
| US-20250290137-A1 | SUBSTITUTED COUMARIN DYES AND USES AS FLUORESCENT LABELS | FBL, DUT, PHAX | SMN1; SMN2 4563/4885KDM4E 3407/4885GRIN1 4848/4885 |
| US-20240271209-A1 | SUBSTITUTED COUMARIN DYES AND USES AS FLUORESCENT LABELS | FBL, DUT, PHAX | SMN1; SMN2 4563/4885KDM4E 3407/4885GRIN1 4848/4885 |
| US-12351871-B2 | Substituted coumarin dyes and uses as fluorescent labels | FBL, DUT, PHAX | SMN1; SMN2 4563/4885KDM4E 3407/4885GRIN1 4848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.