SCHEMBL254392

SCHEMBL254392

CC(=O)O[C@H]1C=C[C@@H](O)C1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.38
CA9 Q16790 4/20 0.38
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
TSHR P16473 2/20 0.33
ALOX15 P16050 1/20 0.32
CHRM2 P08172 4/20 0.31
CHRM4 P08173 4/20 0.31
CHRM1 P11229 4/20 0.31
CHRM3 P20309 4/20 0.31
CHRM5 P08912 2/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9079974 1.00 CA12 (0.38) CA12CA9CA1CA2TSHR
SCHEMBL14472549 1.00 CA12 (0.38) CA12CA9CA1CA2TSHR
SCHEMBL6280678 1.00 CA12 (0.38) CA12CA9CA1CA2TSHR
SCHEMBL1509203 1.00 CA12 (0.38) CA12CA9CA1CA2TSHR
SCHEMBL239520 1.00 CA12 (0.38) CA12CA9CA1CA2TSHR
SCHEMBL307800 1.00 CA12 (0.38) CA12CA9CA1CA2TSHR
SCHEMBL15752289 1.00 CA12 (0.38) CA12CA9CA1CA2TSHR
SCHEMBL8355844 1.00 CA12 (0.38) CA12CA9CA1CA2TSHR
SCHEMBL254386 0.86 CA12 (0.42) CA12CA9CA1CA2TSHR
SCHEMBL11548381 0.86 CA12 (0.42) CA12CA9CA1CA2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 529 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2170791-B1 METHOD FOR PRODUCING CYCLOPENT-4-ENE-1,3-DIOL OR CYCLOPENT-4-ENE-1,3-DIOL DERIVATIVES EUTICALS GMBH (DE) 2013-05-08 EP claimed
US-20100178678-A1 Method for producing cyclopent-4-ene-1,3-diol or cyclopent-4-ene-1,3-diol derivatives ARCHIMICA GMBH (DE) 2010-07-15 US claimed
EP-2170791-A1 METHOD FOR PRODUCING CYCLOPENT-4-ENE-1,3-DIOL OR CYCLOPENT-4-ENE-1,3-DIOL DERIVATIVES Archimica GmbH (DE) 2010-04-07 EP claimed
WO-2008151750-A1 METHOD FOR PRODUCING CYCLOPENT-4-ENE-1,3-DIOL OR CYCLOPENT-4-ENE-1,3-DIOL DERIVATIVES ARCHIMICA GMBH (DE) 2008-12-18 WO claimed
US-20260028316-A1 Biphenyl and Phenylpyridine Compounds PFIZER INC. (US) 2026-01-29 US disclosed
US-20250368611-A1 METHOD FOR PREPARING BERAPROST 314-D SODIUM YS LIFE SCIENCE CO., LTD. (KR) 2025-12-04 US disclosed
US-20250188030-A1 Biphenyl and Phenylpyridine Compounds PFIZER INC. (US) 2025-06-12 US disclosed
US-12173026-B2 PRMT5 inhibitors MERCK SHARP & DOHME LLC (US) 2024-12-24 US disclosed
CN-112805006-B PRMT5 inhibitors 默沙东有限责任公司 2024-09-24 CN disclosed
WO-2024107859-A1 CYCLOPENTENE-OXYMETHYLENE PHOSPHONAMIDATES AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS ROME THERAPEUTICS, INC. (US) 2024-05-23 WO disclosed
EP-4328310-A1 SIRNA TARGETING 17B-HYDROXYSTEROID DEHYDROGENASE TYPE 13 AND SIRNA CONJUGATE Tuojie Biotech (Shanghai) Co., Ltd. (CN) 2024-02-28 EP disclosed
US-20230382932-A1 Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) PFIZER INC. (US) 2023-11-30 US disclosed
EP-0475411-A1 Novel carbocyclic adenosine analogs useful as immunosuppressants HOECHST MARION ROUSSEL, INC. (US) 1992-03-18 EP disclosed
US-5091431-A Hypotensive agents SCHERING CORPORATION (US) 1992-02-25 US disclosed
WO-1991015489-A1 PROCESS FOR THE SYNTHESIS OF CYCLOPENTENE DERIVATIVES GLAXO INC. (US) 1991-10-17 WO disclosed
WO-1991015447-A1 SYNTHESIS OF CYCLOPENTENE DERIVATIVES GLAXO INC. (US) 1991-10-17 WO disclosed
US-5057630-A SYNTHESIS OF CYCLOPENTENE DERIVATIVES GLAXO INC. (US) 1991-10-15 US disclosed
EP-0330004-A1 Nucleoside-type compounds as phosphodiesterase inhibitors SCHERING CORPORATION (US) 1989-08-30 EP disclosed
WO-1989007102-A1 NULCEOSIDETYPE COMPOUNDS WHICH ARE PHOSPHODIESTERASE INHIBITORS SCHERING CORPORATION (US) 1989-08-10 WO disclosed
US-4008125-A New cyclopentene-diols and new acyl esters thereof and process for their preparation TEIJIN LIMITED (JA) 1977-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250368611-A1 METHOD FOR PREPARING BERAPROST 314-D SODIUM CYP11B2, CYP11B1, VIP CA12 1271/4885CA9 1472/4885CA1 1571/4885
US-20250188030-A1 Biphenyl and Phenylpyridine Compounds CYP1B1, CYP1A1, PAH CA12 4556/4885CA9 2280/4885CA1 4296/4885
US-20100178678-A1 Method for producing cyclopent-4-ene-1,3-diol or cyclopent-4-ene-1,3-diol derivatives OTUB1, DEK, DECR1 CA12 1107/4885CA9 760/4885CA1 216/4885
US-12173026-B2 PRMT5 inhibitors PRMT5, PRMT1, PRMT3 CA12 4317/4885CA9 3118/4885CA1 3572/4885
US-20230382932-A1 Cyclopentane-Based Modulators of STING (Stimulator of Interferon Genes) STING1, IRF3, CGAS CA12 4767/4885CA9 4568/4885CA1 4872/4885
US-20260028316-A1 Biphenyl and Phenylpyridine Compounds KAT2B, KAT2A, KAT6A CA12 3995/4885CA9 3985/4885CA1 4083/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.