Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.89 |
| ▸ | CA4 | P22748 | 2/20 | 0.89 |
| ▸ | CES1 | P23141 | 3/20 | 0.55 |
| ▸ | CES2 | O00748 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | DAO | P14920 | 1/20 | 0.55 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 11/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL11789341 | 0.97 | CA2 (0.94) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL188041 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL1445056 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL29624 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL457494 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL4525348 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL944537 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL20570232 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL20570059 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR | |
| Benzoic Acid SCHEMBL1798863 | 0.94 | CA2 (0.89) | CA2CA4CES1CES2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103038360-A | Method for determining protease in biological sample | PAPST LICENSING GMBH & CO KG | 2013-04-10 | — | — | CN | claimed |
| US-4022804-A | ADDITION REACTION; SULFONIC ACID BROMIDES, UNSATURATED COMPOUNDS | BASF AKTIENGESELLSCHAFT (DT) | 1977-05-10 | — | — | US | claimed |
| CN-113149933-B | Compound, preparation method thereof and application of compound as energetic material | 西安固能新材料科技有限公司 | 2025-05-06 | — | — | CN | disclosed |
| US-20230256236-A1 | TRANSFORMABLE NEEDLE FOR ELECTROPORATION | GRAND DECADE DEVELOPMENTS LIMITED (HK) | 2023-08-17 | — | — | US | disclosed |
| WO-2021262989-A1 | TRANSFORMABLE NEEDLE FOR ELECTROPORATION | ONCOSEC MEDICAL INCORPORATED (US) | 2021-12-30 | — | — | WO | disclosed |
| CN-108347878-B | Improved method for treating liquid waste fractions from animal waste | 废品绿化有限责任公司 | 2021-10-29 | — | — | CN | disclosed |
| WO-2021158685-A1 | HEMOSTATIC COMBINATION THERAPY WITH LOW VOLTAGE ELECTROPORATION | ONCOSEC MEDICAL INCORPORATED (US) | 2021-08-12 | — | — | WO | disclosed |
| EP-3787665-A1 | ELECTROPORATION SYSTEMS, METHODS, AND APPARATUS | OncoSec Medical Incorporated (US) | 2021-03-10 | — | — | EP | disclosed |
| US-20200316376-A1 | ELECTROPORATION SYSTEMS, METHODS, AND APPARATUS | GRAND DECADE DEVELOPMENTS LIMITED (HK) | 2020-10-08 | — | — | US | disclosed |
| US-20200318255-A1 | FAR-INFRARED, THz NANOCRYSTALS, HETEROSTRUCTURED MATERIAL WITH INTRABAND ABSORPTION FEATURE AND USES THEREOF | NEXDOT (FR) | 2020-10-08 | — | — | US | disclosed |
| EP-3692186-A1 | FAR-INFRARED, THz NANOCRYSTALS, HETEROSTRUCTURED MATERIAL WITH INTRABAND ABSORPTION FEATURE AND USES THEREOF | Nexdot (FR) | 2020-08-12 | — | — | EP | disclosed |
| WO-1999032514-A2 | SAG: SENSITIVE TO APOPTOSIS GENE | WARNER-LAMBERT COMPANY (US) | 1999-07-01 | — | — | WO | disclosed |
| WO-1999006101-A1 | METHOD AND APPARATUS FOR USING ELECTROPORATION MEDIATED DELIVERY OF DRUGS AND GENES | GENETRONICS, INC. (US) | 1999-02-11 | — | — | WO | disclosed |
| EP-0456686-B1 | EXCRETORY/SECRETORY ANTIGENS OF TAPEWORM (CYSTICERCUS CELLULOSAE) FOR USE IN IMMUNODIAGNOSIS AND VACCINE PREPARATION | ASTRA AB (SE) | 1996-03-20 | — | — | EP | disclosed |
| US-5212069-A | Forming dipeptides from amides and glycine, cysteine or methionine | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1993-05-18 | — | — | US | disclosed |
| US-5134073-A | Culture product of zoogloea ramigera | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1992-07-28 | — | — | US | disclosed |
| EP-0456686-A1 | EXCRETORY/SECRETORY ANTIGENS OF TAPEWORM (CYSTICERCUS CELLULOSAE) FOR USE IN IMMUNODIAGNOSIS AND VACCINE PREPARATION. | ASTRA AB (SE) | 1991-11-21 | — | — | EP | disclosed |
| US-5047506-A | Method for the purification of factor XIII by affinity chromatography | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1991-09-10 | — | — | US | disclosed |
| WO-1990008958-A1 | EXCRETORY/SECRETORY ANTIGENS OF TAPEWORM (CYSTICERCUS CELLULOSAE) FOR USE IN IMMUNODIAGNOSIS AND VACCINE PREPARATION | AKTIEBOLAGET ASTRA (SE) | 1990-08-09 | — | — | WO | disclosed |
| US-4022804-A | ADDITION REACTION; SULFONIC ACID BROMIDES, UNSATURATED COMPOUNDS | BASF AKTIENGESELLSCHAFT (DT) | 1977-05-10 | — | — | US | disclosed |