Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25443110 | 0.88 | MAPT (0.35) | MAPTTSHRSMN1; SMN2OPRL1TRPV1 | |
| SCHEMBL25442286 | 0.82 | OPRL1 (0.41) | TSHRSMN1; SMN2OPRL1OPRM1CHRM2 | |
| SCHEMBL25442289 | 0.76 | ERAP1 (0.39) | MAPTSMN1; SMN2 | |
| SCHEMBL23903375 | 0.72 | SMN1; SMN2 (0.44) | MAPTTSHRSMN1; SMN2OPRL1MEN1 | |
| SCHEMBL25442296 | 0.72 | SMN1; SMN2 (0.42) | MAPTTSHRSMN1; SMN2OPRL1MEN1 | |
| SCHEMBL23903359 | 0.71 | SMN1; SMN2 (0.45) | MAPTTSHRSMN1; SMN2TRPV1 | |
| SCHEMBL25442273 | 0.71 | SMN1; SMN2 (0.46) | MAPTTSHRSMN1; SMN2OPRL1MEN1 | |
| SCHEMBL25442283 | 0.70 | OPRL1 (0.40) | MAPTTSHRSMN1; SMN2OPRL1MEN1 | |
| SCHEMBL23903361 | 0.69 | NPSR1 (0.41) | MAPTTSHRSMN1; SMN2OPRL1OPRM1 | |
| SCHEMBL25442288 | 0.69 | OPRL1 (0.41) | TSHRSMN1; SMN2OPRL1OPRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230142739-A1 | PROTEIN-PROTEIN INTERACTION STABILIZERS | UNIV CALIFORNIA (US) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230142739-A1 | PROTEIN-PROTEIN INTERACTION STABILIZERS | HSPBP1, HSPA8, HSPH1 | MAPT 1086/4885TSHR 3608/4885SMN1; SMN2 1672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.