Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25443736 | 0.97 | ADAMTS5 (0.43) | ADAMTS5SMN1; SMN2DRD2DRD3ALDH1A1 | |
| SCHEMBL25443734 | 0.96 | ADAMTS5 (0.42) | ADAMTS5SMN1; SMN2DRD2DRD3ALDH1A1 | |
| SCHEMBL25443735 | 0.96 | ADAMTS5 (0.42) | ADAMTS5SMN1; SMN2DRD2DRD3ALDH1A1 | |
| SCHEMBL25443738 | 0.93 | ADAMTS5 (0.43) | ADAMTS5DRD2DRD3MAPK1KCNH2 | |
| SCHEMBL25443739 | 0.86 | SLC9A1 (0.46) | DRD3ALDH1A1KCNH2HRH3KMO | |
| SCHEMBL25444220 | 0.86 | DRD3 (0.48) | ADAMTS5SMN1; SMN2DRD2DRD3ALDH1A1 | |
| SCHEMBL25443731 | 0.80 | MAPT (0.51) | ADAMTS5SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL25443730 | 0.76 | MAPT (0.53) | ADAMTS5SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL15840473 | 0.76 | ADAMTS5 (0.58) | ADAMTS5SMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL25443729 | 0.76 | MAPT (0.52) | ADAMTS5SMN1; SMN2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230146870-A1 | METHOD TO QUANTIFY AFFINITY AND SELECTIVITY OF SMALL MOLECULES FOR PROTEINS IN LIVING CELLS | OHIO STATE INNOVATION FOUNDATION | 2023-05-11 | — | — | US | disclosed |