Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25443734 | 1.00 | ADAMTS5 (0.42) | ADAMTS5ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL25443736 | 0.99 | ADAMTS5 (0.43) | ADAMTS5ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL25443737 | 0.96 | ADAMTS5 (0.41) | ADAMTS5ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL25443738 | 0.91 | ADAMTS5 (0.43) | ADAMTS5MAPK1DRD2DRD3ADAM17 | |
| SCHEMBL25444220 | 0.90 | DRD3 (0.48) | ADAMTS5ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL25443739 | 0.84 | SLC9A1 (0.46) | ALDH1A1DRD3 | |
| SCHEMBL25443727 | 0.81 | MAPT (0.52) | ADAMTS5ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL25443729 | 0.81 | MAPT (0.52) | ADAMTS5ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL25443730 | 0.79 | MAPT (0.53) | ADAMTS5ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL25444217 | 0.77 | GNAI3 (0.48) | DRD2DRD3NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230146870-A1 | METHOD TO QUANTIFY AFFINITY AND SELECTIVITY OF SMALL MOLECULES FOR PROTEINS IN LIVING CELLS | OHIO STATE INNOVATION FOUNDATION | 2023-05-11 | — | — | US | disclosed |
| US-20230146870-A1 | METHOD TO QUANTIFY AFFINITY AND SELECTIVITY OF SMALL MOLECULES FOR PROTEINS IN LIVING CELLS | OHIO STATE INNOVATION FOUNDATION | 2023-05-11 | — | — | US | disclosed |