Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA4 | P22748 | 3/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25447454 | 0.85 | CA2 (0.59) | NPC1RAB9AKMT2ACA2CA4 | |
| SCHEMBL25447366 | 0.85 | CA2 (0.52) | NPC1RAB9AKMT2ACA2CA4 | |
| SCHEMBL25447148 | 0.85 | MEN1 (0.49) | NPC1RAB9AKMT2AMEN1CA2 | |
| SCHEMBL25447231 | 0.83 | CA2 (0.50) | HIF1ANPC1RAB9ACA2CA4 | |
| SCHEMBL31683861 | 0.83 | NPC1 (0.53) | HIF1ANPC1RAB9AKMT2AMEN1 | |
| SCHEMBL28635599 | 0.83 | NPC1 (0.53) | HIF1ANPC1RAB9AKMT2AMEN1 | |
| SCHEMBL25446974 | 0.83 | P2RX7 (0.52) | HIF1ACNR1P2RX7 | |
| SCHEMBL25447261 | 0.83 | MAPT (0.56) | NPC1RAB9AKMT2AMEN1CA2 | |
| SCHEMBL25447310 | 0.81 | MAPT (0.51) | KMT2ASMN1; SMN2 | |
| SCHEMBL25447001 | 0.81 | NPC1 (0.52) | NPC1RAB9AKMT2AMEN1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078915-A1 | BIS(HETERO)ARYL THIOETHER (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-05-11 | — | — | WO | disclosed |