Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8278235 | 0.78 | TDP1 (0.43) | ALDH1A1TDP1HSD17B10CTSDTSHR | |
| SCHEMBL7294193 | 0.78 | TSHR (0.43) | ALDH1A1TDP1HSD17B10CTSDTSHR | |
| SCHEMBL20124844 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TDP1HSD17B10CTSDTSHR | |
| SCHEMBL21034656 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TDP1HSD17B10CTSDTSHR | |
| SCHEMBL5549485 | 0.76 | ALDH1A1 (0.39) | ALDH1A1TDP1HSD17B10CTSDTSHR | |
| SCHEMBL8426023 | 0.72 | ALDH1A1 (0.36) | ALDH1A1TDP1HSD17B10CTSDTSHR | |
| SCHEMBL21326414 | 0.72 | ALDH1A1 (0.36) | ALDH1A1TDP1HSD17B10CTSDTSHR | |
| SCHEMBL8757357 | 0.71 | TSHR (0.48) | ALDH1A1TDP1HSD17B10CTSDTSHR | |
| SCHEMBL11059719 | 0.69 | TDP1 (0.33) | ALDH1A1TDP1HSD17B10CTSDTSHR | |
| Hydrochloric Acid SCHEMBL9003482 | 0.69 | TSHR (0.46) | ALDH1A1TDP1HSD17B10CTSDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560634-A1 | NITRIC OXIDE RELEASING PRODRUGS OF THERAPEUTIC AGENTS | Piramal Enterprises Limited (IN) | 2013-02-27 | — | — | EP | claimed |
| WO-2011132171-A1 | NITRIC OXIDE RELEASING PRODRUGS OF THERAPEUTIC AGENTS | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-10-27 | — | — | WO | claimed |
| US-20110263526-A1 | Nitric Oxide Releasing Prodrugs of Therapeutic Agents | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-10-27 | — | — | US | claimed |
| EP-4404974-A1 | ANTIBODY-DRUG CONJUGATES | Spirea Limited (GB) | 2024-07-31 | — | — | EP | disclosed |
| WO-2023218243-A1 | LAG-3/PD-L1 BINDING FUSION PROTEINS | AVACTA LIFE SCIENCES LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023047090-A1 | ANTIBODY-DRUG CONJUGATES | SPIREA LIMITED (GB) | 2023-03-30 | — | — | WO | disclosed |
| CN-115666653-A | Antibody-drug conjugates | 斯皮雷亚有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-112204047-A | PD-L1 binding adhesins and uses related thereto | 阿瓦克塔生命科学有限公司 | 2021-01-08 | — | — | CN | disclosed |
| CN-105307687-A | Multimodal silica-based nanoparticles | SLOAN KETTERING INST CANCER | 2016-02-03 | — | — | CN | disclosed |
| CN-102245214-B | Biodegradable polymer-bioactive moiety conjugates | POLYACTIVA PTY LTD. (AU) | 2014-10-29 | — | — | CN | disclosed |
| EP-2560634-A1 | NITRIC OXIDE RELEASING PRODRUGS OF THERAPEUTIC AGENTS | Piramal Enterprises Limited (IN) | 2013-02-27 | — | — | EP | disclosed |
| WO-2011132171-A1 | NITRIC OXIDE RELEASING PRODRUGS OF THERAPEUTIC AGENTS | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-10-27 | — | — | WO | disclosed |
| US-20110263526-A1 | Nitric Oxide Releasing Prodrugs of Therapeutic Agents | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-10-27 | — | — | US | disclosed |
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |
| US-4404069-A | Electrolytic desulfurization of anilino sulfur compounds | MONSANTO COMPANY (US) | 1983-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263526-A1 | Nitric Oxide Releasing Prodrugs of Therapeutic Agents | NOS2, NOS1, NOS3 | ALDH1A1 204/4885TDP1 1017/4885HSD17B10 1049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.