Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2596501 | 1.00 | C5AR1 (0.52) | C5AR1KDM4EATMNPSR1TDP1 | |
| SCHEMBL786060 | 0.84 | C5AR1 (0.50) | C5AR1KDM4EATMNPSR1TDP1 | |
| SCHEMBL22273283 | 0.83 | KDM4E (0.43) | C5AR1KDM4EATMNPSR1TDP1 | |
| SCHEMBL1543208 | 0.82 | KDM4E (0.47) | C5AR1KDM4EATMNPSR1TDP1 | |
| Oxalic Acid SCHEMBL7908190 | 0.79 | C5AR1 (0.54) | C5AR1LMNAGRIN2BTSHR | |
| SCHEMBL3376962 | 0.78 | YTHDC1 (0.58) | KDM4EATMNPSR1TDP1YTHDC1 | |
| SCHEMBL21595356 | 0.78 | KDM4E (0.44) | C5AR1KDM4EATMNPSR1TDP1 | |
| SCHEMBL21595355 | 0.78 | KDM4E (0.44) | C5AR1KDM4EATMNPSR1TDP1 | |
| SCHEMBL5517424 | 0.78 | KDM4E (0.45) | C5AR1KDM4EATMNPSR1TDP1 | |
| SCHEMBL1435742 | 0.78 | KDM4E (0.48) | KDM4EATMNPSR1TDP1YTHDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12011490-B2 | Dental photocurable composition excellent in operability and storage stability | SHOFU INC. (JP) | 2024-06-18 | — | — | US | disclosed |
| US-20220401312-A1 | DENTAL PHOTOCURABLE COMPOSITION EXCELLENT IN OPERABILITY AND STORAGE STABILITY | SHOFU INC. (JP) | 2022-12-22 | — | — | US | disclosed |
| EP-4062895-A1 | DENTAL PHOTOCURABLE COMPOSITION EXCELLENT IN OPERABILITY AND STORAGE STABILITY | Shofu Inc. (JP) | 2022-09-28 | — | — | EP | disclosed |
| US-20220287918-A1 | DENTAL ADHESIVE COMPOSITION EXCELLENT IN STORAGE STABILITY | SHOFU INC. (JP) | 2022-09-15 | — | — | US | disclosed |
| EP-4056163-A1 | DENTAL ADHESIVE COMPOSITION EXCELLENT IN STORAGE STABILITY | Shofu Inc. (JP) | 2022-09-14 | — | — | EP | disclosed |
| EP-3558964-B1 | 4-AMINO-2-PYRIDO-BICYCLIC PYRIMIDINES AND USE THEREOF AS TOPOISOMERASE II INHIBITORS | FONDAZIONE ST ITALIANO TECNOLOGIA (IT) | 2022-05-04 | — | — | EP | disclosed |
| EP-3558964-B1 | 4-AMINO-2-PYRIDO-BICYCLIC PYRIMIDINES AND USE THEREOF AS TOPOISOMERASE II INHIBITORS | FONDAZIONE ST ITALIANO TECNOLOGIA (IT) | 2022-05-04 | — | — | EP | disclosed |
| US-10889560-B2 | 4-amino-2-pyrido-bicyclic pyrimidines and use thereof as topoisomerase II inhibitors | UNIVERSITÀ DEGLI STUDI DI PADOVA (IT) | 2021-01-12 | — | — | US | disclosed |
| US-10889560-B2 | 4-amino-2-pyrido-bicyclic pyrimidines and use thereof as topoisomerase II inhibitors | UNIVERSITÀ DEGLI STUDI DI PADOVA (IT) | 2021-01-12 | — | — | US | disclosed |
| EP-2013175-B9 | p38 MAP KINASE INHIBITORS | MACROPHAGE PHARMA LTD (GB) | 2020-11-11 | — | — | EP | disclosed |
| US-20110098282-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-04-28 | — | — | US | disclosed |
| US-20090099185-A1 | P38 Map Kinase Inhibitors | CHROMA THERAPEUTICS LTD. (GB) | 2009-04-16 | — | — | US | disclosed |
| US-20090099185-A1 | P38 Map Kinase Inhibitors | CHROMA THERAPEUTICS LTD. (GB) | 2009-04-16 | — | — | US | disclosed |
| US-20090099185-A1 | P38 Map Kinase Inhibitors | CHROMA THERAPEUTICS LTD. (GB) | 2009-04-16 | — | — | US | disclosed |
| WO-2009021944-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-02-19 | — | — | WO | disclosed |
| EP-2013175-A1 | p38 MAP KINASE INHIBITORS | Chroma Therapeutics Limited (GB) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007129040-A1 | p38 MAP KINASE INHIBITORS | CHROMA THERAPEUTICS LTD. (GB) | 2007-11-15 | — | — | WO | disclosed |
| WO-2007129040-A1 | p38 MAP KINASE INHIBITORS | CHROMA THERAPEUTICS LTD. (GB) | 2007-11-15 | — | — | WO | disclosed |
| US-6211219-B1 | DRUGS, ANALGESICS AND AGONISTS | MERCK SHARP & DOHME LTD. (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0638553-A1 | Carboxylic acid amides having a terminal carboxylic acid group as aggregation inhibiting drugs | Dr. Karl Thomae GmbH (DE) | 1995-02-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099185-A1 | P38 Map Kinase Inhibitors | MAPK1, CNKSR1, MAPK3 | C5AR1 94/4885KDM4E 4343/4885ATM 2157/4885 |
| US-12011490-B2 | Dental photocurable composition excellent in operability and storage stability | H1-0, CCND1, CCNT1 | C5AR1 1140/4885KDM4E 1526/4885ATM 794/4885 |
| US-20220287918-A1 | DENTAL ADHESIVE COMPOSITION EXCELLENT IN STORAGE STABILITY | ITGA1, ITGB1, CDH1 | C5AR1 272/4885KDM4E 2130/4885ATM 938/4885 |
| US-20110098282-A1 | NEW COMPOUNDS | BRDT, AURKAIP1, ABCG2 | C5AR1 3330/4885KDM4E 3077/4885ATM 4112/4885 |
| US-20220401312-A1 | DENTAL PHOTOCURABLE COMPOSITION EXCELLENT IN OPERABILITY AND STORAGE STABILITY | H1-0, CCND1, CCNT1 | C5AR1 1163/4885KDM4E 1344/4885ATM 774/4885 |
| US-10889560-B2 | 4-amino-2-pyrido-bicyclic pyrimidines and use thereof as topoisomerase II inhibitors | TYMP, TYMS, TOP2A | C5AR1 2686/4885KDM4E 486/4885ATM 1039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.