Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.47 |
| ▸ | CHKA | P35790 | 4/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 3/20 | 0.37 |
| ▸ | CSF1R | P07333 | 3/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.34 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4667357 | 0.88 | ALDH1A1 (0.43) | KCNH2SCN5ASCN9AEGFRKDR | |
| SCHEMBL25453064 | 0.83 | GRIA1 (0.37) | KCNH2SCN5ASCN9AEGFRGRM5 | |
| SCHEMBL25453079 | 0.83 | EGFR (0.48) | CHKARXRAEGFRCSF1RKDR | |
| SCHEMBL30502771 | 0.83 | EGFR (0.46) | CHKARXRAEGFRCSF1RKDR | |
| SCHEMBL25453063 | 0.83 | EGFR (0.46) | CHKARXRAEGFRCSF1RKDR | |
| SCHEMBL3658312 | 0.74 | ADORA2A (0.44) | LMNAMAPTALOX15TSHR | |
| SCHEMBL28358475 | 0.74 | CYP2D6 (0.51) | KCNH2SCN5ASCN9ACHKAKDR | |
| SCHEMBL25175471 | 0.73 | ALDH1A1 (0.47) | KCNH2EGFRKDRGRM5LMNA | |
| SCHEMBL22453198 | 0.72 | ALDH1A1 (0.54) | KCNH2SCN5ASCN9ACHKALMNA | |
| SCHEMBL4731660 | 0.70 | KCNH2 (0.40) | KCNH2SCN5ASCN9ARXRAPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081800-A1 | ALPHA-2A ADRENERGIC RECEPTOR MODULATORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-05-11 | — | — | WO | disclosed |