Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4667357 | 0.88 | ALDH1A1 (0.43) | ALDH1A1HSD17B10NPC1MEN1KMT2A | |
| SCHEMBL25453062 | 0.83 | KCNH2 (0.47) | LMNAMAPTHPGDALOX15EGFR | |
| SCHEMBL25453079 | 0.83 | EGFR (0.48) | ALDH1A1MEN1KMT2AMAPK1MAPT | |
| SCHEMBL12669556 | 0.83 | ALDH1A1 (0.37) | ALDH1A1HSD17B10MAPTSMN1; SMN2CYP3A4 | |
| SCHEMBL25175471 | 0.83 | ALDH1A1 (0.47) | ALDH1A1HSD17B10LMNAMAPTCYP3A4 | |
| SCHEMBL3658312 | 0.74 | ADORA2A (0.44) | ALDH1A1HSD17B10MEN1KMT2AMAPK1 | |
| SCHEMBL17602105 | 0.74 | GRIA1 (0.52) | GRIA1ALDH1A1HSD17B10NPC1MEN1 | |
| SCHEMBL30502771 | 0.73 | EGFR (0.46) | ALDH1A1EGFRGRM5 | |
| SCHEMBL25453063 | 0.73 | EGFR (0.46) | ALDH1A1EGFRGRM5 | |
| SCHEMBL29187152 | 0.69 | OPRD1 (0.39) | ALDH1A1SMN1; SMN2ASIC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081800-A1 | ALPHA-2A ADRENERGIC RECEPTOR MODULATORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-05-11 | — | — | WO | disclosed |