Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | PDE7A | Q13946 | 12/20 | 0.58 |
| ▸ | PDE7B | Q9NP56 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CCR2 | P41597 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8669659 | 0.85 | PDE7A (0.61) | MAPK1TSHRPDE7APDE7BKMT2A | |
| SCHEMBL2777612 | 0.82 | PDE7A (0.55) | MAPK1TSHRPDE7APDE7BLMNA | |
| SCHEMBL20150186 | 0.81 | TSHR (0.64) | TSHRLMNAKMT2AALDH1A1MAPT | |
| SCHEMBL2847249 | 0.81 | PDE7A (0.57) | MAPK1TSHRPDE7APDE7BLMNA | |
| SCHEMBL11150115 | 0.80 | TDP1 (0.62) | MAPK1TSHRPDE7APDE7BLMNA | |
| Water SCHEMBL11171597 | 0.79 | TSHR (0.47) | MAPK1TSHRPDE7APDE7BLMNA | |
| SCHEMBL4963975 | 0.79 | PDE7A (0.82) | MAPK1TSHRPDE7APDE7BLMNA | |
| SCHEMBL2935849 | 0.78 | BACE1 (0.45) | MAPK1TSHRKMT2AALDH1A1 | |
| SCHEMBL5423544 | 0.78 | PDE7A (0.42) | MAPK1TSHRPDE7APDE7BLMNA | |
| SCHEMBL1151368 | 0.78 | ATM (0.58) | MAPK1TSHRPDE7AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808164-A | Process for producing aromatic sulfides | PHILLIPE PETROLEUM COMPANY (US) | 1998-09-15 | — | — | US | claimed |
| US-5618981-A | Process for producing aromatic sulfides | PHILLIPS PETROLEUM COMPANY (US) | 1997-04-08 | — | — | US | claimed |
| US-10000471-B2 | Pyrazole P38 map kinase inhibitors | RESPIVERT LIMITED (GB) | 2018-06-19 | — | — | US | disclosed |
| US-10000471-B2 | Pyrazole P38 map kinase inhibitors | RESPIVERT LIMITED (GB) | 2018-06-19 | — | — | US | disclosed |
| US-20170362208-A1 | NOVEL COMPOUNDS | RESPIVERT LIMITED (GB) | 2017-12-21 | — | — | US | disclosed |
| US-20170362208-A1 | NOVEL COMPOUNDS | RESPIVERT LIMITED (GB) | 2017-12-21 | — | — | US | disclosed |
| US-20170362208-A1 | NOVEL COMPOUNDS | RESPIVERT LIMITED (GB) | 2017-12-21 | — | — | US | disclosed |
| US-9771354-B2 | Pyrazole p38 map kinase inhibitors | RESPIVERT LTD. (GB) | 2017-09-26 | — | — | US | disclosed |
| US-9771354-B2 | Pyrazole p38 map kinase inhibitors | RESPIVERT LTD. (GB) | 2017-09-26 | — | — | US | disclosed |
| US-9771354-B2 | Pyrazole p38 map kinase inhibitors | RESPIVERT LTD. (GB) | 2017-09-26 | — | — | US | disclosed |
| US-20160130256-A1 | NOVEL COMPOUNDS | RESPIVERT LIMITED (GB) | 2016-05-12 | — | — | US | disclosed |
| US-20130029990-A1 | PYRAZOLE P38 MAP KINASE INHIBITORS | RESPIVERT LTD. (GB) | 2013-01-31 | — | — | US | disclosed |
| US-20130029990-A1 | PYRAZOLE P38 MAP KINASE INHIBITORS | RESPIVERT LTD. (GB) | 2013-01-31 | — | — | US | disclosed |
| WO-2011121366-A1 | PYRAZOLE P38 MAP KINASE INHIBITORS | RESPIVERT LIMITED (GB) | 2011-10-06 | — | — | WO | disclosed |
| WO-2011121366-A1 | PYRAZOLE P38 MAP KINASE INHIBITORS | RESPIVERT LIMITED (GB) | 2011-10-06 | — | — | WO | disclosed |
| US-5808164-A | Process for producing aromatic sulfides | PHILLIPE PETROLEUM COMPANY (US) | 1998-09-15 | — | — | US | disclosed |
| US-5618981-A | Process for producing aromatic sulfides | PHILLIPS PETROLEUM COMPANY (US) | 1997-04-08 | — | — | US | disclosed |
| US-4349377-A | Phenoxyphenylthioalkanecarboxylic acid amides and their use as herbicides and plant growth regulants | CIBA-GEIGY CORPORATION (US) | 1982-09-14 | — | — | US | disclosed |
| EP-0000359-B1 | PHENOXY-PHENYLSULFINYL-AND-SULFONYLALKANECARBOXYLIC ACID DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS. | CIBA-GEIGY AG (CH) | 1981-10-21 | — | — | EP | disclosed |
| EP-0000351-A1 | Phenoxy-phenyl-thio-alkanecarboxylic acid derivatives method for their preparation and their use as herbicides and plant growth regulators | CIBA-GEIGY AG (CH) | 1979-01-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362208-A1 | NOVEL COMPOUNDS | ARG1, IL1B, LTB4R | MAPK1 2401/4885TSHR 1021/4885PDE7A 3376/4885 |
| US-10000471-B2 | Pyrazole P38 map kinase inhibitors | MAPK1, MAP3K1, MAPK3 | MAPK1 1/4885TSHR 1144/4885PDE7A 1532/4885 |
| US-20160130256-A1 | NOVEL COMPOUNDS | ARG1, IL1B, LTB4R | MAPK1 2401/4885TSHR 1021/4885PDE7A 3376/4885 |
| US-20130029990-A1 | PYRAZOLE P38 MAP KINASE INHIBITORS | MAPK1, MAP3K1, MAPK3 | MAPK1 1/4885TSHR 1216/4885PDE7A 1595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.