SCHEMBL2545668

SCHEMBL2545668

PC(=Cc1ccccc1-c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 2/20 0.42
GRIN3B O60391 2/20 0.42
GRIN1 Q05586 2/20 0.42
GRIN2A Q12879 2/20 0.42
GRIN2B Q13224 2/20 0.42
GRIN2C Q14957 2/20 0.42
GRIN3A Q8TCU5 2/20 0.42
ALDH1A1 P00352 4/20 0.39
HSD17B10 Q99714 2/20 0.39
HPGD P15428 1/20 0.39
BCL2L1 Q07817 1/20 0.39
BACE1 P56817 2/20 0.36
CYP2A6 P11509 1/20 0.34
MAPK1 P28482 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL828196 0.80 GRIN2D (0.44) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL29801710 0.80 GRIN2D (0.44) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL28304106 0.74 CYP19A1 (0.41) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL10049286 0.74 GRIN2D (0.46) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL9441680 0.74 GRIN2D (0.46) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL4108379 0.72 TP53 (0.52) ALDH1A1BCL2L1MAPK1HDAC2HDAC6
SCHEMBL2841427 0.71 GRIN2D (0.50) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
Bromide SCHEMBL29160890 0.70 CYP19A1 (0.54) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL21352355 0.70 AKR1C1 (0.50) ALDH1A1HPGDMAPK1L3MBTL1
SCHEMBL380916 0.70 AKR1C1 (0.50) ALDH1A1HPGDMAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112439460-B Immobilized rhodium-based catalyst and preparation method and application thereof 中国石油化工股份有限公司 2023-02-28 CN claimed
US-4092466-A Heat resistant polymers of oxidized styrylphosphine NASA 1978-05-30 US claimed
CN-118043294-A SiC P-type and low resistivity crystals, boules, wafers and devices and methods of making the same 帕里杜斯有限公司 2024-05-14 CN disclosed
CN-117957635-A SiC P-type and low resistivity crystals, boules, wafers and devices and methods of making the same 帕里杜斯有限公司 2024-04-30 CN disclosed
CN-117916850-A SiC P-type and low resistivity crystals, boules, wafers and devices and methods of making the same 帕里杜斯有限公司 2024-04-19 CN disclosed
CN-112439460-B Immobilized rhodium-based catalyst and preparation method and application thereof 中国石油化工股份有限公司 2023-02-28 CN disclosed
CN-114031889-B High-temperature-resistant ABS composite material and preparation method thereof 湖州伟悦高分子材料有限公司 2022-06-07 CN disclosed
CN-114031889-A High-temperature-resistant ABS composite material and preparation method thereof 湖州伟悦高分子材料有限公司 2022-02-11 CN disclosed
CN-112439460-A Immobilized rhodium-based catalyst and preparation method and application thereof 中国石油化工股份有限公司 2021-03-05 CN disclosed
CN-111732844-A Household fireproof coating and preparation method thereof 高雪梅 2020-10-02 CN disclosed
CN-111363287-A High-strength antistatic flame-retardant plastic and preparation method thereof 湖南七纬科技有限公司 2020-07-03 CN disclosed
US-20130165667-A1 METHOD FOR THE PREPARATION OF PHOSPHINE BUTADIENE LIGANDS, COMPLEXES THEREOF WITH COPPER AND USE THEREOF IN CATALYSIS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2013-06-27 US disclosed
US-8426647-B2 2013-04-23 US disclosed
EP-2552928-A1 A PROCESS FOR THE REDUCTION OF A TERTIARY PHOSPHINE OXIDE TO THE CORRESPONDING TERTIARY PHOSPHINE IN THE PRESENCE OF A CATALYST AND USE OF A TERTIARY PHOSPHINE FOR REDUCING A TERTIARY PHOSPHINE OXIDE IN THE PRESENCE OF A CATALYST Chromafora AB (SE) 2013-02-06 EP disclosed
US-20130012725-A1 PROCESS FOR THE REDUCTION OF A TERTIARY PHOSPHINE OXIDE TO THE CORRESPONDING TERTIARY PHOSPHINE IN THE PRESENCE OF A CATALYST AND USE OF A TERTIARY PHOSPHINE FOR REDUCING A TERTIARY PHOSPHINE OXIDE IN THE PRESENCE OF A CATALYST CHROMAFORA AB (SE) 2013-01-10 US disclosed
WO-2011123037-A1 A PROCESS FOR THE REDUCTION OF A TERTIARY PHOSPHINE OXIDE TO THE CORRESPONDING TERTIARY PHOSPHINE IN THE PRESENCE OF A CATALYST AND USE OF A TERTIARY PHOSPHINE FOR REDUCING A TERTIARY PHOSPHINE OXIDE IN THE PRESENCE OF A CATALYST CHROMAFORA AB (SE) 2011-10-06 WO disclosed
US-20100121076-A1 METHOD FOR THE PREPARATION OF PHOSPHINE BUTADIENE LIGANDS, COMPLEXES THEREOF WITH COPPER AND USE THEREOF IN CATALYSIS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2010-05-13 US disclosed
US-4200721-A Heat resistant polymers of oxidized styrylphosphine NASA 1980-04-29 US disclosed
US-4168287-A MONOMER FOR FLAME-RESISTANT, NONTOXIC POLYMERS NASA 1979-09-18 US disclosed
US-4092466-A Heat resistant polymers of oxidized styrylphosphine NASA 1978-05-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130165667-A1 METHOD FOR THE PREPARATION OF PHOSPHINE BUTADIENE LIGANDS, COMPLEXES THEREOF WITH COPPER AND USE THEREOF IN CATALYSIS BCHE, DOHH, AOC1 GRIN2D 3829/4885GRIN3B 3882/4885GRIN1 4158/4885
US-20100121076-A1 METHOD FOR THE PREPARATION OF PHOSPHINE BUTADIENE LIGANDS, COMPLEXES THEREOF WITH COPPER AND USE THEREOF IN CATALYSIS PDXK, AOC1, PNPO GRIN2D 3011/4885GRIN3B 2964/4885GRIN1 3598/4885
US-20130012725-A1 PROCESS FOR THE REDUCTION OF A TERTIARY PHOSPHINE OXIDE TO THE CORRESPONDING TERTIARY PHOSPHINE IN THE PRESENCE OF A CATALYST AND USE OF A TERTIARY PHOSPHINE FOR REDUCING A TERTIARY PHOSPHINE OXIDE IN THE PRESENCE OF A CATALYST PSPH, PNPO, PHOSPHO1 GRIN2D 4177/4885GRIN3B 3407/4885GRIN1 2944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.