⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25457 | 0.68 | — | — | |
| SCHEMBL4971091 | 0.68 | — | — | |
| SCHEMBL20393983 | 0.68 | — | — | |
| SCHEMBL9453839 | 0.67 | SLC22A6 (0.40) | — | |
| SCHEMBL1716494 | 0.66 | — | — | |
| SCHEMBL8486263 | 0.65 | USP2 (0.41) | — | |
| SCHEMBL198521 | 0.59 | — | — | |
| SCHEMBL749954 | 0.59 | — | — | |
| SCHEMBL9294980 | 0.58 | GABRP (0.43) | — | |
| SCHEMBL5133855 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7635572-B2 | Methods for conducting assays for enzyme activity on protein microarrays | Life Technologies Corporation (US) | 2009-12-22 | — | — | US | disclosed |
| EP-1642109-A4 | METHODS FOR CONDUCTING ASSAYS FOR ENZYME ACTIVITY ON PROTEIN MICROARRAYS | PROTOMETRIX INC (US) | 2007-09-05 | — | — | EP | disclosed |
| EP-1642109-A2 | METHODS FOR CONDUCTING ASSAYS FOR ENZYME ACTIVITY ON PROTEIN MICROARRAYS | Protometrix, Inc. (US) | 2006-04-05 | — | — | EP | disclosed |
| US-20050118665-A1 | Methods for conducting assays for enzyme activity on protein microarrays | PROTOMETRIX, INC. | 2005-06-02 | — | — | US | disclosed |
| WO-2005003721-A2 | ENZYME ACTIVITY ASSAYS ON PROTEIN MICROARRAYS | PROTOMETRIX, INC. (US) | 2005-01-13 | — | — | WO | disclosed |