Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CA3 | P07451 | 1/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.57 |
| ▸ | CA6 | P23280 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24795771 | 0.87 | ACHE (0.43) | CA2CA12CA1CA9LMNA | |
| SCHEMBL19119200 | 0.82 | ENPP1 (0.47) | CA2CA12CA1CA9LMNA | |
| SCHEMBL19141722 | 0.82 | ACHE (0.47) | LMNAACHESMN1; SMN2MAPTKDM4E | |
| SCHEMBL9122304 | 0.79 | ACHE (0.51) | MAOBACHESMN1; SMN2MAPTKDM4E | |
| SCHEMBL19141923 | 0.79 | ACHE (0.47) | LMNAACHESMN1; SMN2MAPTKDM4E | |
| SCHEMBL19141926 | 0.79 | ACHE (0.43) | CA2ACHESMN1; SMN2MAPTKDM4E | |
| SCHEMBL11798029 | 0.79 | MAPT (0.51) | LMNAACHESMN1; SMN2MAPTKDM4E | |
| SCHEMBL25459991 | 0.78 | ALDH1A1 (0.47) | LMNAMAOBACHESMN1; SMN2MAPT | |
| SCHEMBL7317657 | 0.78 | LMNA (0.62) | CA2CA12CA1CA9LMNA | |
| SCHEMBL7307801 | 0.78 | LMNA (0.62) | CA2CA12CA1CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4180090-A1 | BENZISOXAZOLE DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2023-05-17 | — | — | EP | disclosed |