Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | CA2 | P00918 | 3/20 | 0.62 |
| ▸ | CA12 | O43570 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.62 |
| ▸ | CA9 | Q16790 | 2/20 | 0.62 |
| ▸ | CA3 | P07451 | 1/20 | 0.62 |
| ▸ | CA4 | P22748 | 1/20 | 0.62 |
| ▸ | CA6 | P23280 | 1/20 | 0.62 |
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | CA5A | P35218 | 1/20 | 0.62 |
| ▸ | CA7 | P43166 | 1/20 | 0.62 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.62 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316085 | 0.89 | CA12 (0.65) | LMNACA2CA12CA1CA9 | |
| SCHEMBL7315256 | 0.86 | LMNA (0.45) | LMNACA2CA12CA1CA9 | |
| SCHEMBL2615285 | 0.86 | LMNA (0.45) | LMNACA2CA12CA1CA9 | |
| SCHEMBL24795775 | 0.86 | LMNA (0.45) | LMNACA2CA12CA1CA9 | |
| SCHEMBL2615284 | 0.86 | LMNA (0.45) | LMNACA2CA12CA1CA9 | |
| SCHEMBL7314652 | 0.81 | CA2 (0.62) | LMNACA2CA12CA1CA9 | |
| SCHEMBL7317657 | 0.81 | LMNA (0.62) | LMNACA2CA12CA1CA9 | |
| SCHEMBL25459999 | 0.78 | CA2 (0.57) | LMNACA2CA12CA1CA9 | |
| SCHEMBL13180387 | 0.77 | MAPT (0.44) | LMNAMAPTTDP1HTR2ASCD | |
| Zonisamide SCHEMBL4427407 | 0.77 | LMNA (1.00) | LMNACA2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172896-A | ANTICONVULSANTS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1979-10-30 | — | — | US | claimed |
| EP-4180090-A1 | BENZISOXAZOLE DERIVATIVE | Sumitomo Pharma Co., Ltd. (JP) | 2023-05-17 | — | — | EP | disclosed |
| WO-2010081036-A2 | FLUORINE CONTAINING COMPOUNDS AND METHODS OF USE THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-07-15 | — | — | WO | disclosed |
| US-4172896-A | ANTICONVULSANTS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1979-10-30 | — | — | US | disclosed |