Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 6/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 6/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25460803 | 0.83 | GAA (0.41) | PDK1PDK2PDK3PDK4TP53 | |
| SCHEMBL1626611 | 0.81 | NOTUM (0.40) | PDK1PDK2PDK3PDK4GAA | |
| SCHEMBL1626668 | 0.81 | PLCG1 (0.44) | PDK1PDK2PDK3PDK4GAA | |
| SCHEMBL25464178 | 0.79 | EPHX2 (0.43) | RAB9AKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL25460829 | 0.76 | GAA (0.47) | PDK1PDK2PDK3PDK4GAA | |
| SCHEMBL1626474 | 0.74 | ALDH1A1 (0.42) | MAPTPOLBKDM4EALDH1A1KMT2A | |
| SCHEMBL31619473 | 0.73 | PDK1 (0.41) | PDK1PDK2PDK3PDK4GAA | |
| SCHEMBL30148352 | 0.73 | PDK1 (0.39) | PDK1PDK2PDK3PDK4GAA | |
| SCHEMBL8225791 | 0.73 | CA2 (0.44) | PDK1PDK2PDK3PDK4GAA | |
| SCHEMBL31560752 | 0.71 | LMNA (0.37) | PDK1PDK2PDK3PDK4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151074-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151074-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | GIPR, GLP1R, GCGR | PDK1 1840/4885PDK2 2856/4885PDK3 2605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.