SCHEMBL25461671

SCHEMBL25461671

c1ccc2c(-c3cccc4oc5cccnc5c34)ncnc2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.43
KDM4E B2RXH2 3/20 0.38
MAPT P10636 3/20 0.38
ALDH1A1 P00352 2/20 0.38
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
PDE4D Q08499 2/20 0.35
PI4KA P42356 1/20 0.35
PI4K2B Q8TCG2 1/20 0.35
PI4K2A Q9BTU6 1/20 0.35
PI4KB Q9UBF8 1/20 0.35
PDE4A P27815 1/20 0.35
PDE4B Q07343 1/20 0.35
PDE4C Q08493 1/20 0.35
NCOA1 Q15788 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
GRM4 Q14833 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25461669 0.86 LMNA (0.38) KDM4EMAPTALDH1A1GAAHPGD
SCHEMBL26266958 0.86 ADORA2A (0.50) ADORA2AKDM4EMAPTALDH1A1HPGD
SCHEMBL25461252 0.80 KDM4E (0.48) KDM4EMAPTALDH1A1GAAHPGD
SCHEMBL29381921 0.79 LMNA (0.49) ADORA2AKDM4EMAPTALDH1A1PDE4D
SCHEMBL25462078 0.77 ADORA2A (0.42) ADORA2AKDM4EMAPTALDH1A1PDE4D
SCHEMBL24596447 0.77 ADK (0.47) ADORA2AKDM4EMAPTALDH1A1HPGD
SCHEMBL24796189 0.75 ADORA2A (0.45) ADORA2AKDM4EMAPTALDH1A1GAA
SCHEMBL25461666 0.74 KDM4E (0.40) KDM4EMAPTALDH1A1GAAHPGD
SCHEMBL25461672 0.74 KDM4E (0.42) KDM4EMAPTALDH1A1GAAHPGD
SCHEMBL18232956 0.73 TOP1 (0.42) KDM4EMAPTALDH1A1GAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230151020-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) 2023-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230151020-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE OCIAD1, OCIAD2, EHD1 ADORA2A 3563/4885KDM4E 2555/4885MAPT 2164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.