SCHEMBL254638

SCHEMBL254638

O=C(N[C@@H](Cc1c[nH]cn1)C(=O)O)OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 12/20 0.53
ITGA2B P08514 12/20 0.53
CTSL P07711 3/20 0.49
CTSB P07858 3/20 0.49
CTSS P25774 3/20 0.49
MME P08473 1/20 0.49
ECE1 P42892 1/20 0.49
TACR1 P25103 2/20 0.49
ITGAV P06756 1/20 0.48
IDO1 P14902 1/20 0.48
TDO2 P48775 1/20 0.48
CTSK P43235 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24795018 1.00 ITGB3 (0.53) ITGB3ITGA2BCTSLCTSBCTSS
SCHEMBL4178755 1.00 ITGB3 (0.53) ITGB3ITGA2BCTSLCTSBCTSS
SCHEMBL10443977 0.93 CTSL (0.57) ITGB3ITGA2BCTSLCTSBCTSS
SCHEMBL7263839 0.93 ITGB3 (0.48) ITGB3ITGA2BCTSLCTSBCTSS
Dl-Phenylalanine SCHEMBL28362972 0.92 ITGB3 (0.52) ITGB3ITGA2BCTSLCTSBCTSS
SCHEMBL27506310 0.91 CTSL (0.51) ITGB3ITGA2BCTSLCTSBCTSS
SCHEMBL29401219 0.91 ALDH1A1 (0.54) CTSLCTSBCTSSTACR1CTSK
SCHEMBL29576042 0.90 CTSK (0.50) CTSLCTSBCTSSMMEECE1
SCHEMBL7938093 0.90 CAPN1 (0.60) CTSLCTSBCTSSCTSK
SCHEMBL9828822 0.89 MAPK1 (0.45) ITGB3ITGA2BMMEECE1ITGAV

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118616094-A Artificial enzyme with laccase-like catalytic activity, and preparation method and application thereof 天津大学 2024-09-10 CN claimed
CN-117946287-B Preparation method and application of antibacterial amino acid-based cellulose polymer 江苏惠利生物科技有限公司 2024-06-11 CN claimed
CN-117946287-A Preparation method and application of antibacterial amino acid-based cellulose polymer 江苏惠利生物科技有限公司 2024-04-30 CN claimed
CN-116726241-B Collagen hemostatic and antibacterial dressing and preparation method thereof 江苏亨瑞生物医药科技有限公司 2023-10-20 CN claimed
CN-116726241-A Collagen hemostatic and antibacterial dressing and preparation method thereof 江苏亨瑞生物医药科技有限公司 2023-09-12 CN claimed
CN-112898204-B Synthesis method of N-carbobenzoxy-L-histidine 苏州昊帆生物股份有限公司 2023-05-12 CN claimed
CN-116082565-A Self-assembled oxidation mimic enzyme material and preparation method and application thereof 北京化工大学 2023-05-09 CN claimed
CN-114133398-B Amino acid substituted acyclovir tricyclic nucleoside derivative and synthesis method and application thereof 中南民族大学 2022-11-22 CN claimed
CN-114133398-A Amino acid substituted acyclovir tricyclic nucleoside derivative and synthesis method and application thereof 中南民族大学 2022-03-04 CN claimed
US-11246822-B2 Biomedical composition for skin care and/or maintenance and delaying and/or inhibiting skin aging and the use thereof INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2022-02-15 US claimed
US-7229973-B2 pH-sensitive polymeric micelles for drug delivery UTAH, UNIVERSITY OF RESEARCH FOUNDATION 2007-06-12 US claimed
US-20050070721-A1 PH-sensitive polymeric micelles for drug delivery UNIVERSITY OF UTAH RESEARCH FOUNDATION 2005-03-31 US claimed
EP-0540626-A1 PROCESS FOR SYNTHESIZING PEPTIDES EASTMAN CHEMICAL COMPANY (US) 1993-05-12 EP claimed
WO-1992001709-A1 PROCESS FOR SYNTHESIZING PEPTIDES EASTMAN KODAK COMPANY (US) 1992-02-06 WO claimed
CN-121698812-A Preparation method of N-Cbz-L-histidine 安徽昊帆生物有限公司 2026-03-20 CN disclosed
CN-121698812-A Preparation method of N-Cbz-L-histidine 安徽昊帆生物有限公司 2026-03-20 CN disclosed
CN-120607488-A Preparation method of N-Cbz-L-histidyl hydrazide 淮安昊帆生物医药有限公司 2025-09-09 CN disclosed
EP-0144290-A2 Substituted ethylenediamine derivatives CIBA-GEIGY AG (CH) 1985-06-12 EP disclosed
EP-0105193-A2 Spergualin-related compounds, processes for the preparation thereof and their use as medicaments MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) 1984-04-11 EP disclosed
US-4338309-A AMINOGLYCOSIDE ANTIBIOTICS ABBOTT LABORATORIES (US) 1982-07-06 US disclosed