Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.45 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16866144 | 0.84 | NPC1 (0.86) | RAB9ANPC1POLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL25464496 | 0.81 | RAB9A (0.60) | RAB9ANPC1POLBLMNAALDH1A1 | |
| SCHEMBL23573491 | 0.80 | NPC1 (0.77) | RAB9ANPC1POLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL23573490 | 0.80 | NPC1 (0.77) | RAB9ANPC1POLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL2750640 | 0.79 | RAB9A (0.97) | RAB9ANPC1POLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL25464452 | 0.79 | KMT2A (0.64) | RAB9ANPC1POLBSMN1; SMN2GAA | |
| SCHEMBL27267057 | 0.78 | RAB9A (1.00) | RAB9ANPC1POLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL27264917 | 0.78 | RAB9A (1.00) | RAB9ANPC1POLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL25464475 | 0.77 | SMN1; SMN2 (0.63) | RAB9ANPC1SMN1; SMN2ALDH1A1PRMT3 | |
| SCHEMBL9273863 | 0.75 | NPC1 (0.70) | RAB9ANPC1POLBL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230151074-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230151074-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | GIPR, GLP1R, GCGR | RAB9A 658/4885NPC1 2460/4885POLB 4809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.