Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | RAB9A | P51151 | 3/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16866144 | 0.89 | NPC1 (0.86) | NPC1RAB9APOLBL3MBTL1LMNA | |
| SCHEMBL23573490 | 0.84 | NPC1 (0.77) | NPC1RAB9APOLBL3MBTL1LMNA | |
| SCHEMBL23573491 | 0.84 | NPC1 (0.77) | NPC1RAB9APOLBL3MBTL1LMNA | |
| SCHEMBL2750640 | 0.84 | RAB9A (0.97) | NPC1RAB9APOLBL3MBTL1LMNA | |
| SCHEMBL27267057 | 0.82 | RAB9A (1.00) | NPC1RAB9APOLBL3MBTL1LMNA | |
| SCHEMBL27264917 | 0.82 | RAB9A (1.00) | NPC1RAB9APOLBL3MBTL1LMNA | |
| SCHEMBL4983290 | 0.81 | L3MBTL1 (0.76) | NPC1RAB9APOLBL3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL1326683 | 0.76 | NPC1 (0.57) | NPC1RAB9APOLBL3MBTL1LMNA | |
| SCHEMBL25464492 | 0.75 | RAB9A (0.64) | NPC1RAB9APOLBL3MBTL1LMNA | |
| SCHEMBL1418851 | 0.75 | RAB9A (0.63) | NPC1RAB9APOLBL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420164-A | Enzyme inhibitors | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0507291-A1 | Cyclohexylurea compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |