Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23420674 | 0.79 | TSHR (0.39) | TSHRALDH1A1 | |
| SCHEMBL25468424 | 0.78 | — | — | |
| SCHEMBL27765547 | 0.77 | TSHR (0.37) | TSHRALDH1A1 | |
| SCHEMBL460923 | 0.77 | TSHR (0.42) | TSHRALDH1A1 | |
| SCHEMBL10355634 | 0.77 | TSHR (0.37) | TSHRALDH1A1 | |
| SCHEMBL23420249 | 0.75 | TSHR (0.36) | TSHRALDH1A1 | |
| SCHEMBL7937540 | 0.75 | MEN1 (0.38) | TSHRALDH1A1 | |
| SCHEMBL23420800 | 0.75 | ZDHHC20 (0.39) | TSHRALDH1A1 | |
| SCHEMBL867543 | 0.74 | ZDHHC20 (0.37) | TSHRALDH1A1THRATHRB | |
| SCHEMBL14376299 | 0.74 | PIN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230148061-A1 | TEAD INHIBITORS AND USES THEREOF | THE EHE FOUNDATION | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230148061-A1 | TEAD INHIBITORS AND USES THEREOF | TEAD2, TEAD3, TEAD4 | TSHR 4635/4885ALDH1A1 1195/4885THRA 3728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.