SCHEMBL25469331

SCHEMBL25469331

Cc1cc(O)cc(C)c1C[C@@H](C)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.41
ACHE P22303 1/20 0.41
OPRK1 P41145 5/20 0.39
OPRM1 P35372 4/20 0.38
OPRD1 P41143 3/20 0.38
FFAR1 O14842 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6264063 1.00 CYP3A4 (0.41) CYP3A4ACHEOPRK1OPRM1OPRD1
SCHEMBL14032468 1.00 CYP3A4 (0.41) CYP3A4ACHEOPRK1OPRM1OPRD1
SCHEMBL10608422 0.79 SLC7A5 (0.50) CYP3A4OPRK1OPRM1OPRD1
SCHEMBL296690 0.79 SLC7A5 (0.50) CYP3A4OPRK1OPRM1OPRD1
SCHEMBL23964694 0.79 OPRM1 (0.43) CYP3A4OPRM1
SCHEMBL38374 0.79 SLC7A5 (0.50) CYP3A4OPRK1OPRM1OPRD1
Bromide SCHEMBL10477399 0.78 SLC7A5 (0.49) CYP3A4OPRK1OPRM1OPRD1
Hydrochloric Acid SCHEMBL10477430 0.78 SLC7A5 (0.49) CYP3A4OPRK1OPRM1OPRD1
Hydrochloric Acid SCHEMBL10421601 0.78 SLC7A5 (0.49) CYP3A4OPRK1OPRM1OPRD1
Bromide SCHEMBL10477401 0.78 SLC7A5 (0.49) CYP3A4OPRK1OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795196-B2 Mitochondria-targeting peptides STEALTH BIOTHERAPEUTICS INC. (US) 2023-10-24 US disclosed
US-20230146515-A1 MITOCHONDRIA-TARGETING PEPTIDES STEALTH BIOTHERAPEUTICS INC. 2023-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11795196-B2 Mitochondria-targeting peptides HSPE1, TFAM, TNNI3 CYP3A4 4834/4885ACHE 4821/4885OPRK1 3460/4885
US-20230146515-A1 MITOCHONDRIA-TARGETING PEPTIDES HSPE1, TFAM, TNNI3 CYP3A4 4834/4885ACHE 4821/4885OPRK1 3460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.