Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.34 |
| ▸ | TMPRSS15 | P98073 | 5/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24802237 | 0.81 | GABRR1 (0.33) | OPRM1GABRR1PRSS1TMPRSS15FFAR4 | |
| SCHEMBL14032468 | 0.79 | CYP3A4 (0.41) | OPRM1CYP3A4 | |
| SCHEMBL7136191 | 0.79 | APAF1 (0.41) | GABRR1PRSS1TMPRSS15KDM4EAPAF1 | |
| SCHEMBL25469331 | 0.79 | CYP3A4 (0.41) | OPRM1CYP3A4 | |
| SCHEMBL6264063 | 0.79 | CYP3A4 (0.41) | OPRM1CYP3A4 | |
| SCHEMBL19750294 | 0.78 | TAAR1 (0.50) | OPRM1TAAR1 | |
| SCHEMBL296982 | 0.78 | USP2 (0.53) | TAAR1CYP3A4CYP2C9KDM4EPOLB | |
| SCHEMBL296983 | 0.78 | USP2 (0.53) | TAAR1CYP3A4CYP2C9KDM4EPOLB | |
| SCHEMBL26379094 | 0.77 | CHRNA7 (0.44) | GABRR1APPCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9067390 | 0.75 | ALDH1A1 (0.39) | CYP2C9FFAR4KDM4EAPAF1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021216529-A1 | β-ARRESTIN EFFECTORS AND COMPOSITIONS AND METHODS OF USE THEREOF | TREVENA, INC. (US) | 2021-10-28 | — | — | WO | disclosed |