Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.32 |
| ▸ | CDK8 | P49336 | 3/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24005739 | 0.78 | MAPT (0.33) | FGFR1KDRTNIKCDK8BRD4 | |
| SCHEMBL25650900 | 0.78 | LPAR1 (0.33) | FGFR1KDRCDK8BRD4 | |
| SCHEMBL25613032 | 0.77 | FEN1 (0.38) | FGFR1KDRBRD4CFTR | |
| SCHEMBL19820203 | 0.73 | KLKB1 (0.43) | FGFR1KDRLRRK2CDK8 | |
| SCHEMBL24005702 | 0.71 | MAP4K1 (0.37) | FGFR1KDRCDK8 | |
| SCHEMBL30400588 | 0.66 | AXL (0.37) | BRD4 | |
| SCHEMBL26176322 | 0.66 | AXL (0.37) | BRD4 | |
| SCHEMBL24005759 | 0.66 | FGFR1 (0.39) | FGFR1KDRLRRK2CDK8BRD4 | |
| SCHEMBL6493825 | 0.64 | NUDT1 (0.41) | KDRLRRK2CDK8 | |
| SCHEMBL25469866 | 0.64 | TTK (0.35) | FGFR1KDRCDK8BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078398-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2023-05-11 | — | — | WO | disclosed |