Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25791703 | 0.66 | KDR (0.36) | — | |
| SCHEMBL28979830 | 0.66 | KDR (0.33) | SMPD3 | |
| SCHEMBL13960990 | 0.66 | KDR (0.37) | — | |
| SCHEMBL25791708 | 0.64 | TGFBR2 (0.51) | — | |
| SCHEMBL25097592 | 0.64 | KDR (0.32) | — | |
| SCHEMBL19237242 | 0.63 | SMPD3 (0.48) | CRHR1SMPD3 | |
| SCHEMBL24767177 | 0.62 | KDM4E (0.43) | — | |
| SCHEMBL23728532 | 0.62 | ALDH1A1 (0.55) | — | |
| SCHEMBL16848725 | 0.60 | HCAR3 (0.39) | HCAR3 | |
| SCHEMBL12781461 | 0.60 | HCAR3 (0.38) | HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081212-A1 | METHODS OF USING ALK2 INHIBITORS | KEROS THERAPEUTICS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |