SCHEMBL25474697

SCHEMBL25474697

CC(C)CCCCNC(=S)Nc1ccc(CC(C)C)cc1

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 9/20 0.57
MAPT P10636 6/20 0.57
ALOX12 P18054 1/20 0.57
KMT2A Q03164 6/20 0.53
SMN1; SMN2 Q16637 5/20 0.53
ALDH1A1 P00352 5/20 0.53
HTT P42858 4/20 0.53
MEN1 O00255 3/20 0.53
RECQL P46063 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
GLA P06280 1/20 0.51
HPGD P15428 1/20 0.47
GAA P10253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17972729 0.85 SMN1; SMN2 (0.65) LMNAMAPTALOX12KMT2ASMN1; SMN2
SCHEMBL25474694 0.83 TRPV1 (0.43) LMNAMAPTALOX12KMT2ASMN1; SMN2
SCHEMBL25474698 0.83 EPHX1 (0.53) LMNAMAPTSMN1; SMN2ALDH1A1HTT
SCHEMBL9453900 0.81 SMN1; SMN2 (0.51) LMNAMAPTALOX12SMN1; SMN2ALDH1A1
SCHEMBL15739655 0.79 P2RY6 (0.75) LMNAMAPTALOX12KMT2ASMN1; SMN2
SCHEMBL21338327 0.78 LMNA (0.51) LMNAMAPTALOX12KMT2ASMN1; SMN2
SCHEMBL3976381 0.77 ALDH1A1 (0.58) LMNAMAPTALOX12KMT2ASMN1; SMN2
SCHEMBL24778058 0.75 RAB9A (0.61) MAPTSMN1; SMN2ALDH1A1HPGDGAA
SCHEMBL25473525 0.74 HDAC3 (0.57) MAPTSMN1; SMN2GAA
SCHEMBL24312063 0.73 LMNA (0.49) LMNAMAPTALOX12KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230149569-A1 MULTIFUNCTIONAL COMPOUNDS FOR USE IN MEDICAL IMAGING AND THERAPY ANTELOPE SURGICAL SOLUTIONS, INC. 2023-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230149569-A1 MULTIFUNCTIONAL COMPOUNDS FOR USE IN MEDICAL IMAGING AND THERAPY PAICS, BID, OGFR LMNA 3739/4885MAPT 466/4885ALOX12 1570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.