SCHEMBL25478404

SCHEMBL25478404

CC1CN(I)C(c2ccccc2C(C)C)CO1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NR3C2 P08235 3/20 0.32
GLRA1 P23415 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24005867 0.84 NR3C2 (0.32) NR3C2GLRA1
SCHEMBL25613530 0.81 NR3C2 (0.31) NR3C2
SCHEMBL25478279 0.77 ADRB2 (0.36)
SCHEMBL25478281 0.75 NSD2 (0.34)
SCHEMBL25478451 0.75 NSD2 (0.35)
SCHEMBL25478218 0.74 OPRM1 (0.32)
SCHEMBL6276897 0.72 TSHR (0.41)
SCHEMBL25478249 0.72
SCHEMBL25478605 0.71 HTR2A (0.40)
SCHEMBL25628587 0.70 ADRB2 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023088167-A1 COMPOUNDS AS BCL-2 INHIBITORS FOCHON PHARMACEUTICALS, LTD. (CN) 2023-05-25 WO disclosed