Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25478281 | 0.85 | NSD2 (0.34) | NSD2G6PDCCR6OPRM1OPRK1 | |
| SCHEMBL25478218 | 0.83 | OPRM1 (0.32) | OPRM1OPRK1GABRA1GABRB2ALOX15 | |
| SCHEMBL24005469 | 0.79 | OPRM1 (0.36) | NSD2G6PDCCR6OPRM1OPRK1 | |
| SCHEMBL24005468 | 0.77 | ACHE (0.38) | OPRM1OPRK1GABRA1GABRB2CNR2 | |
| SCHEMBL24005867 | 0.76 | NR3C2 (0.32) | OPRM1OPRK1GABRA1GABRB2SLC6A2 | |
| SCHEMBL25478404 | 0.75 | NR3C2 (0.32) | — | |
| SCHEMBL31610743 | 0.74 | GABRA1 (0.39) | GABRA1GABRB2SLC6A2 | |
| SCHEMBL17297749 | 0.74 | GABRA1 (0.39) | GABRA1GABRB2SLC6A2 | |
| SCHEMBL25478279 | 0.74 | ADRB2 (0.36) | GABRA1GABRB2 | |
| SCHEMBL25478605 | 0.71 | HTR2A (0.40) | OPRM1OPRK1HTR7SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088167-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2023-05-25 | — | — | WO | disclosed |