Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24005484 | 0.84 | P2RX7 (0.39) | ITGB2ICAM1ITGALKIF11IRAK4 | |
| SCHEMBL25629272 | 0.81 | ITGB2 (0.38) | ITGB2ICAM1ITGALKIF11IRAK4 | |
| SCHEMBL25628689 | 0.78 | ITGB2 (0.36) | ITGB2ICAM1ITGALKIF11IRAK4 | |
| SCHEMBL25492873 | 0.74 | ITGB2 (0.37) | ITGB2ICAM1ITGALKIF11IRAK4 | |
| SCHEMBL24005504 | 0.70 | P2RX7 (0.41) | ITGB2ICAM1ITGALCYP3A4MEN1 | |
| SCHEMBL25478787 | 0.69 | KMT2A (0.38) | ITGB2ICAM1ITGALKIF11CYP3A4 | |
| SCHEMBL25628690 | 0.69 | MEN1 (0.38) | KIF11CYP3A4MEN1KMT2ACYP2D6 | |
| SCHEMBL25480483 | 0.68 | MEN1 (0.34) | MEN1KMT2AALOX15TDP1 | |
| SCHEMBL25478789 | 0.68 | P2RX7 (0.40) | KIF11CYP3A4MEN1KMT2ACYP2D6 | |
| SCHEMBL25628893 | 0.68 | PKM (0.38) | MEN1KMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023088167-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2023-05-25 | — | — | WO | disclosed |