Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.38 |
| ▸ | ITGAL | P20701 | 2/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24005504 | 0.86 | P2RX7 (0.41) | P2RX7ITGB2ICAM1ITGALCYP3A4 | |
| SCHEMBL25480482 | 0.84 | ITGB2 (0.36) | ITGB2ICAM1ITGALKIF11IRAK4 | |
| SCHEMBL25629272 | 0.84 | ITGB2 (0.38) | ITGB2ICAM1ITGALKIF11IRAK4 | |
| SCHEMBL25478789 | 0.84 | P2RX7 (0.40) | P2RX7KIF11CYP3A4MEN1KMT2A | |
| SCHEMBL25479247 | 0.82 | ALDH1A1 (0.49) | MEN1KMT2A | |
| SCHEMBL25628689 | 0.81 | ITGB2 (0.36) | ITGB2ICAM1ITGALKIF11IRAK4 | |
| SCHEMBL24005860 | 0.77 | HTR2A (0.42) | CYP3A4MEN1KMT2ACYP2D6CYP2C9 | |
| SCHEMBL25492873 | 0.77 | ITGB2 (0.37) | ITGB2ICAM1ITGALKIF11IRAK4 | |
| SCHEMBL25492876 | 0.74 | HTR7 (0.39) | HTR7L3MBTL1 | |
| SCHEMBL25480477 | 0.74 | HRH3 (0.33) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021223736-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON PHARMACEUTICALS, LTD. (CN) | 2021-11-11 | — | — | WO | disclosed |